Publication Name	World Journal of Stem Cells
Manuscript ID	47498
Country	South Korea

Received	2019-03-19 01:23
Peer-Review Started	2019-03-19 15:05
To Make the First Decision	2019-06-05 06:20
Return for Revision	2019-06-27 01:19
Revised	2019-07-02 01:12
Second Decision	2019-07-23 06:32
Accepted by Journal Editor-in-Chief	2019-07-23 22:07
Accepted by Executive Editor-in-Chief	2019-07-29 20:10
Articles in Press	2019-07-29 20:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-09-29 09:08
Publish the Manuscript Online	2019-10-22 07:13

ISSN	1948-0210 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cell Biology
Manuscript Type	Review
Article Title	Microfluidic three-dimensional cell culture of stem cells for high-throughput analysis
Manuscript Source	Invited Manuscript
All Author List	Jeong Ah Kim, Soohyun Hong and Won Jong Rhee
ORCID	Author(s) ORCID Number Jeong Ah Kim http://orcid.org/0000-0001-6278-6545 Soohyun Hong http://orcid.org/0000-0003-4609-1203 Won Jong Rhee http://orcid.org/0000-0001-7068-2762
Funding Agency and Grant Number
Corresponding Author	Won Jong Rhee, PhD, Associate Professor, Division of Bioengineering, Incheon National University, Incheon National University, 119 Academy-ro, Yeonsu-gu, Incheon 22012, South Korea. wjrhee@inu.ac.kr
Key Words	Stem cell; Microfluidic technology; Three-dimensional cell culture; High-throughput screening; ;
Core Tip	A recent advance of microfluidic techniques using stem cells for high-throughput assay is described. Induced pluripotent stem cells and the innovative organ-on-a-chip or organoid-on-a-chip have led to progress in in vitro drug screening platforms. We summarized the various examples of microfluidic techniques, including organ-on-a-chip or organoid-on-a-chip using stem cells for high-throughput screening and discussed the current challenges and future perspectives of microfluidic technologies in stem cell research.
Publish Date	2019-10-22 07:13
Citation	Kim JA, Hong S, Rhee WJ. Microfluidic three-dimensional cell culture of stem cells for high-throughput analysis. World J Stem Cell 2019; 11(10):803-816
URL	https://www.wjgnet.com/1948-0210/full/v11/i10/803.htm
DOI	https://dx.doi.org/10.4252/wjsc.v11.i10.803

Full Article (PDF)	WJSC-11-803.pdf
Full Article (Word)	WJSC-11-803.docx
Manuscript File	47498-Review.docx
Answering Reviewers	47498-Answering reviewers.pdf
Audio Core Tip	47498-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	47498-Conflict-of-interest statement.pdf
Copyright License Agreement	47498-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	47498-Language certificate.pdf
Peer-review Report	47498-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	47498-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	47498-Scientific misconduct check.pdf
Scientific Editor Work List	47498-Scientific editor work list.pdf
CrossCheck Report	47498-CrossCheck report.pdf