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Articles Published Processes
7/28/2019 10:51:57 AM | Browse: 1009 | Download: 1552
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Received |
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2019-03-19 01:13 |
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Peer-Review Started |
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2019-03-19 03:47 |
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To Make the First Decision |
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2019-04-30 10:23 |
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Return for Revision |
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2019-05-05 01:27 |
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Revised |
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2019-06-13 02:40 |
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Second Decision |
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2019-06-17 10:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-06-23 01:57 |
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Articles in Press |
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2019-06-23 01:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-07-26 06:54 |
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Publish the Manuscript Online |
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2019-07-28 10:51 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Neoadjuvant and adjuvant treatment strategies for hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Clifford Akateh, Sylvester M Black, Lanla F Conteh, Eric D. Miller, Anne Noonan, Eric D Elliott, Timothy M Pawlik, Allan Tsung and Jordan M Cloyd |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jordan M Cloyd, MD, Assistant Professor, Department of Surgery, The Ohio State University, 410 W 10th Ave, N-907, Columbus, OH 43210, United States. jordan.cloyd@osumc.edu |
| Key Words |
Hepatocellular carcinoma; Neoadjuvant therapy; Adjuvant therapy; Neoplasm recurrence; Hepatectomy; Liver cirrhosis |
| Core Tip |
Liver resection is an important curative-intent treatment option for patients with hepatocellular carcinoma (HCC). However, advanced disease, underlying chronic liver disease and/or cirrhosis, limits the proportion of patients who are surgical candidates. Recurrent disease is unfortunately common even after undergoing resection. As such, the benefits of neoadjuvant and adjuvant treatment strategies aimed at improving resectability and decreasing recurrence rates are of great interest. While high-level evidence to guide treatment decision making is lacking, recent advances in locoregional and systemic therapies, including antiviral treatment and immunotherapy, raise the prospect of novel approaches that may improve the outcomes of patients with HCC. |
| Publish Date |
2019-07-28 10:51 |
| Citation |
Akateh C, Black SM, Conteh L, Miller ED, Noonan A, Elliott E, Pawlik TM, Tsung A, Cloyd JM. Neoadjuvant and adjuvant treatment strategies for hepatocellular carcinoma. World J Gastroenterol 2019; 25(28): 3704-3721 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i28/3704.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i28.3704 |
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