Publication Name	World Journal of Gastroenterology
Manuscript ID	4758
Country	Japan

Received	2013-07-21 13:35
Peer-Review Started	2013-07-22 11:33
First Decision by Editorial Office Director
Return for Revision	2013-08-22 18:58
Revised	2013-09-12 08:40
Publication Fee Transferred
Second Decision by Editor	2013-09-29 11:19
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-09-29 22:02
Articles in Press
Edit the Manuscript by Language Editor	2013-11-13 17:29
Typeset the Manuscript	2013-12-09 11:18
Publish the Manuscript Online	2014-01-20 16:41

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Seasonal variations in the onset of ulcerative colitis in Japan
Manuscript Source	Invited Manuscript
All Author List	Shigeo Koido, Toshifumi Ohkusa, Hiroaki Saito, Tetsuji Yokoyama, Tomoyoshi Shibuya, Naoto Sakamoto, Kan Uchiyama, Hiroshi Arakawa, Taro Osada, Akihito Nagahara, Sumio Watanabe and Hisao Tajiri
Funding Agency and Grant Number	Funding Agency Grant Number Grants in Aid for Scientific Research (C) from the Japanese Ministry of Education, Culture, Sports, Science, and Technology 23501289
Corresponding Author	Shigeo Koido, MD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, the Jikei University School of Medicine, 8 Chome-3-1 Kokuryocho, Chiba 277-8564, Japan. shigeo_koido@jikei.ac.jp
Key Words	Japanese population; Onset; Relapse; Seasonal variations; Ulcerative colitis
Core Tip	Monthly seasonality in the symptomatic onset of ulcerative colitis (UC) during October and March was observed in Japan. The onset of symptoms frequently occurred during the winter, whereas relapse of UC particularly occurred in October. Upper respiratory inflammation was one of the main factors responsible for relapse. Therefore, environmental factors associated with winter and spring seasonality may be responsible for triggering the clinical onset of UC in Japan.
Publish Date	2014-01-20 16:41
Citation	Koido S, Ohkusa T, Saito H, Yokoyama T, Shibuya T, Sakamoto N, Uchiyama K, Arakawa H, Osada T, Nagahara A, Watanabe S, Tajiri H. Seasonal variations in the onset of ulcerative colitis in Japan. World J Gastroenterol 2013; 19(47): 9063-9068
URL	http://www.wjgnet.com/1007-9327/full/v19/i47/9063.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i47.9063

Full Article (PDF)	WJG-19-9063.pdf
Manuscript File	4758-Review.doc
Answering Reviewers	4758-Answering reviewers.pdf
Copyright License Agreement	4758-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4758-Language certificate.pdf
Peer-review Report	4758-Peer review(s).pdf
Scientific Editor Work List	4758-Scientific editor work list.doc