Publication Name	World Journal of Gastroenterology
Manuscript ID	4761
Country	Hungary

Received	2013-07-22 08:39
Peer-Review Started	2013-07-22 16:09
To Make the First Decision	2013-09-02 16:26
Return for Revision	2013-09-03 21:34
Revised	2013-09-28 19:19
Second Decision	2013-11-04 17:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-11-05 10:09
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-02-28 12:17
Publish the Manuscript Online	2014-03-18 14:14

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Frequency and prognostic role of mucosal healing in patients with Crohn’s disease and ulcerative colitis after one-year of biological therapy
Manuscript Source	Invited Manuscript
All Author List	Klaudia Farkas, Péter László Lakatos, Mónika Szűcs, Éva Pallagi-Kunstár, Anita Bálint, Ferenc Nagy, Zoltán Szepes, Noémi Vass, Lajos S Kiss, Tibor Wittmann and Tamás Molnár
Funding Agency and Grant Number	Funding Agency Grant Number TAMOP-4.2.2.A-11/1/KONV 2012-0035 TAMOP-4.2.2.A-11/1/KONV 2012-0052 TAMOP-4.2.2.A-11/1/KONV 2012-0073 OTKA Research Proposal PD 105948
Corresponding Author	Tamás Molnár, MD, PhD, First Department of Medicine, University of Szeged, Korányi fasor 8-10, H6720 Szeged, Hungary. molnar.tamas@med.u-szeged.hu
Key Words	Crohn’s disease; Ulcerative colitis; Biological therapy; Endoscopy; Mucosal healing
Core Tip	Mucosal healing has become a subject of renewed interest, as tumor necrosis factor-α blockers have proven their efficacy in inducing and maintaining clinical and endoscopic remission. In this study, mucosal healing was observed in 56% and 32% of Crohn’s disease (CD) and ulcerative colitis (UC) patients. Retreatment with biological therapies was required in 78% of CD patients and in 100% of UC patients, despite achieving mucosal healing within 12 mo. Our results showed that mucosal healing after 12 mo of treatment was not associated with sustained clinical remission.
Publish Date	2014-03-18 14:14
Citation	Farkas K, Lakatos PL, Sz?cs M, Pallagi-Kunstár é, Bálint A, Nagy F, Szepes Z, Vass N, Kiss LS, Wittmann T, Molnár T. Frequency and prognostic role of mucosal healing in patients with Crohn’s disease and ulcerative colitis after one-year of biological therapy. World J Gastroenterol 2014; 20(11): 2995-3001
URL	http://www.wjgnet.com/1007-9327/full/v20/i11/2995.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i11.2995

Full Article (PDF)	WJG-20-2995.pdf
Full Article (Word)	WJG-20-2995.doc
Manuscript File	4761-Review.doc
Answering Reviewers	4761-Answering reviewers.pdf
Copyright License Agreement	4761-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4761-Language certificate.pdf
Peer-review Report	4761-Peer review(s).pdf
Scientific Editor Work List	4761-Scientific editor work list.doc