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Articles Published Processes
8/14/2019 1:31:33 PM | Browse: 927 | Download: 1500
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Received |
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2019-04-01 01:08 |
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Peer-Review Started |
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2019-04-02 00:15 |
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To Make the First Decision |
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2019-04-30 10:30 |
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Return for Revision |
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2019-05-05 03:45 |
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Revised |
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2019-07-12 19:04 |
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Second Decision |
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2019-07-19 09:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-07-19 16:02 |
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Articles in Press |
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2019-07-19 16:02 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-08-14 07:09 |
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Publish the Manuscript Online |
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2019-08-14 13:31 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Helicobacter pylori and cytokine gene variants as predictors of premalignant gastric lesions
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Anca Negovan, Mihaela Iancu, Emoke Fulop and Claudia Banescu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Internal Research Grant from the University of Medicine, Pharmacy, Sciences and Technology of Târgu Mureș |
615/12/17.01.2019 |
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| Corresponding Author |
Mihaela Iancu, MSc, PhD, Lecturer, Department of Medical Informatics and Biostatistics, University of Medicine and Pharmacy "Iuliu Hațieganu", Louis Pasteur, Cluj-Napoca 400349, Romania. miancu@umfcluj.ro |
| Key Words |
Helicobacter pylori; Gastritis; Premalignant; Glandular atrophy; Intestinal metaplasia; Single-nuclear polymorphism |
| Core Tip |
The role of cytokines and their gene variants has been questioned in relation to Helicobacter pylori (H. pylori) gastritis and gastric cancer but only infrequently for preneoplastic lesions. To date, only the single nucleotide polymorphisms IL-10T-819C, IL-8-251, IL-18RAP917997, IL-22 rs1179251, IL1-B-511, IL1-B-3954, IL4R-398 and IL1RN appear to be predictors for premalignant gastric lesion susceptibility. In order to develop preventative strategies, further studies using multivariable models to test the modifying effect of H. pylori infection on the relationship between cytokine gene variants and premalignant lesions or to test the interaction between H. pylori and cytokine gene variants should be considered. |
| Publish Date |
2019-08-14 13:31 |
| Citation |
Negovan A, Iancu M, Fülöp E, Bănescu C. Helicobacter pylori and cytokine gene variants as predictors of premalignant gastric lesions. World J Gastroenterol 2019; 25(30): 4105-4124 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i30/4105.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i30.4105 |
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