Publication Name	World Journal of Gastroenterology
Manuscript ID	47641
Country	China

Received	2019-03-21 03:50
Peer-Review Started	2019-03-21 07:06
To Make the First Decision	2019-04-08 00:29
Return for Revision	2019-04-08 06:34
Revised	2019-04-24 07:42
Second Decision	2019-05-08 08:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-05-08 16:05
Articles in Press	2019-05-08 16:05
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-05-13 00:45
Typeset the Manuscript	2019-05-29 01:40
Publish the Manuscript Online	2019-06-06 08:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Proton pump inhibitors use increases hepatic encephalopathy risk: A systematic review and meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Yun-Jie Ma, Zong-Xun Cao, Yong Li and Shun-Yi Feng
ORCID	Author(s) ORCID Number Yun-Jie Ma http://orcid.org/0000-0002-8572-7537 Zong-Xun Cao http://orcid.org/0000-0002-9086-5723 Yong Li http://orcid.org/0000-0002-2268-6205 Shun-Yi Feng http://orcid.org/0000-0002-6114-7837
Funding Agency and Grant Number
Corresponding Author	Yong Li, MD, Chief Doctor, Doctor, Emergency, Cangzhou Central Hospital, No. 16 Xinhua Road, Yunhe Qu, Cangzhou 061000, Hebei Province, China. ly13333367871@hotmail.com
Key Words	Proton pump inhibitors; Hepatic encephalopathy; Meta-analysis
Core Tip	Several studies have been conducted to explore the association between the use of proton pump inhibitors (PPIs) and hepatic encephalopathy (HE) risk in patients with liver cirrhosis. However, their results were controversial. The current evidence indicates that PPI use increases HE risk in patients with liver cirrhosis. Physicians should ban PPIs use in patients with liver cirrhosis when they are used without specific indications.
Publish Date	2019-06-06 08:31
Citation	Ma YJ, Cao ZX, Li Y, Feng SY. Proton pump inhibitors use increases hepatic encephalopathy risk: A systematic review and meta-analysis. World J Gastroenterol 2019; 25(21): 2675-2682
URL	https://www.wjgnet.com/1007-9327/full/v25/i21/2675.htm
DOI	https://dx.doi.org/10.3748/wjg.v25.i21.2675

Full Article (PDF)	WJG-25-2675.pdf
Full Article (Word)	WJG-25-2675.docx
PRISMA 2009 Checklist	47641-PRISMA-2009-Checklist-revision_1717.docx
Manuscript File	47641-Review_Edited.docx
Answering Reviewers	47641-Answering reviewers.pdf
Audio Core Tip	47641-Audio core tip.mp3
Biostatistics Review Certificate	47641-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	47641-Conflict-of-interest statement.pdf
Copyright License Agreement	47641-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	47641-Language certificate.pdf
Peer-review Report	47641-Peer-review(s).pdf
Scientific Misconduct Check	47641-Google-MA RY-1.png
Scientific Misconduct Check	47641-Google-MA RY-2.png
Scientific Misconduct Check	47641-Scientific misconduct check.pdf
Scientific Editor Work List	47641-Scientific editor work list.pdf