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Articles Published Processes
8/14/2019 1:31:33 PM | Browse: 794 | Download: 1112
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Received |
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2019-03-26 01:44 |
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Peer-Review Started |
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2019-03-26 04:24 |
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To Make the First Decision |
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2019-04-30 10:37 |
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Return for Revision |
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2019-05-05 03:37 |
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Revised |
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2019-07-15 20:04 |
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Second Decision |
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2019-07-19 09:06 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-07-19 16:11 |
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Articles in Press |
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2019-07-19 16:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-08-12 02:00 |
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Publish the Manuscript Online |
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2019-08-14 13:31 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Role of hepatocyte nuclear factor 4-alpha in gastrointestinal and liver diseases
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Dustin E Bosch, Matthew M Yeh and Sayed S Daoud |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Sayed S Daoud, PhD, Associate Professor, Director, Director, Pharmaceutical Sciences, Washington State University, 412 E. Spokane Falls St., Spokane, WA 99210, United States. daoud@wsu.edu |
| Key Words |
Hepatocyte nucelar factor 4-alpha; Liver cirrhosis; Hepatocellular carcinoma; Viral hepatitis; Gastroinstinal tract; Colorectal carcinoma |
| Core Tip |
Our current understanding of the molecular etiology of human liver and gastrointestinal diseases is limited and there is a critical need to explore novel hypotheses and risk factors that may contribute to these diseases. Hepatocyte nuclear factor 4-alpha (HNF4) has been well recognized as an important transcription factor that regulates gene expression involved in the differentiation of liver and gastrointestinal cells. Dysregulation of HNF4 function is associated with many diseases related to these cells. Here we attempt to update our understanding on the role of HNF4 in the pathogenesis of these diseases for use as target for better therapeutic modality. |
| Publish Date |
2019-08-14 13:31 |
| Citation |
Yeh MM, Bosch DE, Daoud SS. Role of hepatocyte nuclear factor 4-alpha in gastrointestinal and liver diseases. World J Gastroenterol 2019; 25(30): 4074-4091 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i30/4074.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i30.4074 |
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