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Articles Published Processes
5/28/2019 9:29:42 AM | Browse: 929 | Download: 1760
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Received |
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2019-03-23 05:45 |
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Peer-Review Started |
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2019-03-25 07:34 |
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To Make the First Decision |
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2019-04-08 00:19 |
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Return for Revision |
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2019-04-08 06:10 |
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Revised |
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2019-04-12 07:24 |
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Second Decision |
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2019-05-08 08:52 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-05-08 16:02 |
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Articles in Press |
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2019-05-08 16:02 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-05-12 20:23 |
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Typeset the Manuscript |
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2019-05-25 07:08 |
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Publish the Manuscript Online |
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2019-05-28 09:29 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Brucea javanica oil emulsion improves the effect of radiotherapy on esophageal cancer cells by inhibiting cyclin D1-CDK4/6 axis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhong-Hua Qiu, Wei-Wei Zhang, Hong-Hua Zhang and Gui-Hua Jiao |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Gui-Hua Jiao, MSc, Chief Nurse, Department of Interventional Therapy, Affiliated Hospital of Jining Medical College, Jining 272100, Shandong Province, China. gdjkdkfk1268@163.com |
| Key Words |
Esophageal cancer; Brucea javanica oil emulsion; Radiosensitizer; Apoptosis; Cyclin D1-CDK4/6 axis |
| Core Tip |
Brucea javanica oil emulsion (BJOE) is a widely used drug against various cancers. However, its anti-cancer effect and the potential as a radiosensitizer have not been explored in esophageal cancer. In this study, BJOE showed a reliable inhibitory effect on growth, migration and invasion of esophageal cancerous cells. And it was demonstrated that the BJOE could be used as a radiosensitizer to promote the apoptosis in esophageal cancerous cells via cyclin D1-CDK4/6 axis. |
| Publish Date |
2019-05-28 09:29 |
| Citation |
Qiu ZH, Zhang WW, Zhang HH, Jiao GH. Brucea javanica oil emulsion improves the effect of radiotherapy on esophageal cancer cells by inhibiting cyclin D1-CDK4/6 axis. World J Gastroenterol 2019; 25(20): 2463-2472 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i20/2463.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i20.2463 |
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