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Articles Published Processes
6/27/2019 6:34:47 AM | Browse: 950 | Download: 1353
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Received |
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2019-03-26 00:25 |
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Peer-Review Started |
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2019-03-28 09:41 |
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To Make the First Decision |
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2019-05-09 00:21 |
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Return for Revision |
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2019-05-09 02:21 |
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Revised |
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2019-05-29 23:39 |
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Second Decision |
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2019-06-10 02:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-06-10 22:07 |
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Articles in Press |
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2019-06-10 22:07 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-06-27 01:08 |
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Publish the Manuscript Online |
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2019-06-27 06:34 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Minireviews |
| Article Title |
Neoadjuvant therapy in the treatment of hilar cholangiocarcinoma: Review of the literature
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Fabio Frosio, Federico Mocchegiani, Grazia Conte, Enrico Dalla Bona, Andrea Vecchi, Daniele Nicolini and Marco Vivarelli |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Federico Mocchegiani, MD, Assistant Professor, Unit of Hepato-pancreato-biliary and Transplant Surgery, Department of Experimental and Clinical Medicine, Polytechnic University of Marche, Via Conca 71, Ancona 60126, Italy. federicomocchegiani@hotmail.com |
| Key Words |
Hilar cholangiocarcinoma; Klatskin tumor; Neoadjuvant treatement; Radiotherapy; Chemotherapy; Hepatic resection; Liver transplantation |
| Core Tip |
Surgery is the only potentially curative treatment for hilar cholangiorcinoma; however, most of the patients are considered not resectable because of the local extent. Neoadjuvant radiochemotherapy is supposed to increase R0 margins rate, or even to allow radical resection for locally advanced tumors, but few studies are available. Moreover, for patients with early stage tumors meeting the Mayo Clinic criteria, neoadjuvant therapy before liver transplantation has produced very good survivals, gaining worldwide acceptance. This is the first review to consider the role of neoadjuvant treatment for hilar cholangiocarcinoma, before resection as well as before liver transplantation. |
| Publish Date |
2019-06-27 06:34 |
| Citation |
Frosio F, Mocchegiani F, Conte G, Dalla Bona E, Vecchi A, Nicolini D, Vivarelli M. Neoadjuvant therapy in the treatment of hilar cholangiocarcinoma: Review of the literature. World J Gastrointest Surg 2019; 11(6): 279-286 |
| URL |
https://www.wjgnet.com/1948-9366/full/v11/i6/279.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v11.i6.279 |
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