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6/28/2019 12:22:27 PM | Browse: 864 | Download: 1200
Publication Name World Journal of Gastroenterology
Manuscript ID 47913
Country Canada
Received
2019-04-01 00:57
Peer-Review Started
2019-04-01 08:07
To Make the First Decision
2019-04-30 10:32
Return for Revision
2019-05-05 03:43
Revised
2019-05-07 22:48
Second Decision
2019-05-17 09:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-05-18 12:41
Articles in Press
2019-05-18 12:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-06-27 08:18
Publish the Manuscript Online
2019-06-28 12:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Clinical characteristics of young patients with early Barrett’s neoplasia
Manuscript Source Unsolicited Manuscript
All Author List Yugo Iwaya, Yuto Shimamura, Kenichi Goda, Enrique Rodriguez de Santiago, John Gerard Coneys, Jeffrey D Mosko, Gabor Kandel, Paul Kortan, Gary May, Marcon Norman and Christopher Teshima
ORCID
Author(s) ORCID Number
Yugo Iwaya http://orcid.org/0000-0002-2269-0132
Yuto Shimamura http://orcid.org/0000-0002-3831-8327
Kenichi Goda http://orcid.org/0000-0002-0350-3151
Enrique Rodriguez de Santiago http://orcid.org/0000-0002-2852-6042
John Gerard Coneys http://orcid.org/0000-0002-6245-0125
Jeffrey D Mosko http://orcid.org/0000-0003-2983-524X
Gabor Kandel http://orcid.org/0000-0003-0016-338X
Paul Kortan http://orcid.org/0000-0001-8586-3005
Gary May http://orcid.org/0000-0001-5589-6420
Marcon Norman http://orcid.org/0000-0003-2799-7982
Christopher Teshima http://orcid.org/0000-0002-5525-8565
Funding Agency and Grant Number
Corresponding Author Yugo Iwaya, MD, PhD, Doctor, Advanced Therapeutic Endoscopy Centre, St Michael’s Hospital, University of Toronto, 30 Bond Street, Toronto M5B 1W8, Ontario, Canada. yiwaya@shinshu-u.ac.jp
Key Words Barrett’s Esophagus; Gastroesophageal reflux disease; Obesity; Esophageal adenocarcinoma; High-grade dysplasia; Guideline; Young patient
Core Tip Esophageal adenocarcinoma (EAC) and high-grade dysplasia (HGD) may appear in young patients with Barrett’s esophagus (BE). To identify clinical characteristics of young patients with Barrett’s neoplasia, we conducted a retrospective analysis. 450 patients with T1 EAC and HGD were identified; 45 (10%) were young patients at age ≤ 50 years. Compared to the older group, young patients were more likely to present with ongoing gastroesophageal reflux disease (GERD) symptoms and to be obese on multivariate analysis. While guidelines recommend BE screening in patients > 50 years of age, younger patients should be considered for screening endoscopy if they suffer from obesity and GERD symptoms.
Publish Date 2019-06-28 12:22
Citation Iwaya Y, Shimamura Y, Goda K, de Santiago ER, Coneys JG, Mosko JD, Kandel G, Kortan P, May G, Marcon N, Teshima C. Clinical characteristics of young patients with early Barrett’s neoplasia. World J Gastroenterol 2019; 25(24): 3069-3078
URL https://www.wjgnet.com/1007-9327/full/v25/i24/3069.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i24.3069
Full Article (PDF) WJG-25-3069.pdf
Full Article (Word) WJG-25-3069.docx
Manuscript File 47913-Review.docx
Answering Reviewers 47913-Answering reviewers.pdf
Audio Core Tip 47913-Audio core tip.mp3
Biostatistics Review Certificate 47913-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 47913-Conflict-of-interest statement.pdf
Copyright License Agreement 47913-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 47913-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 47913-Institutional review board statement.pdf
Peer-review Report 47913-Peer-review(s).pdf
Scientific Misconduct Check 47913-Scientific misconduct check.pdf
Scientific Editor Work List 47913-Scientific editor work list.pdf