Publication Name	World Journal of Gastroenterology
Manuscript ID	4797
Country	Germany

Received	2013-07-24 11:19
Peer-Review Started	2013-07-24 14:01
To Make the First Decision	2013-09-27 16:49
Return for Revision	2013-09-29 17:09
Revised	2013-09-30 22:45
Second Decision	2013-11-29 11:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-11-30 01:22
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-06 11:22
Publish the Manuscript Online	2014-01-19 14:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Topic Highlights
Article Title	Is hepatitis B-virucidal validation of biocides possible with the use of surrogates?
Manuscript Source	Invited Manuscript
All Author List	Andreas Sauerbrei
Funding Agency and Grant Number
Corresponding Author	Dr. Andreas Sauerbrei, Professor, Institute of Virology and Antiviral Chemotherapy, Jena University Clinic, Friedrich Schiller University of Jena, Hans-Knoell-Straße 2, D-07745 Jena, Germany. andreas.sauerbrei@med.uni-jena.de
Key Words	Hepatitis B virus; Surrogate model; Duck hepatitis B virus; Disinfectants; Testing virucidal efficacy
Core Tip	There is a need for disinfectants with proven virucidal activity against the hepatitis B virus (HBV). Feasible HBV infectivity assays are not available; therefore, the establishment of surrogate models for HBV infection is of high importance. This paper reviews the application of the most promising and feasible assay, the use of the duck hepatitis B virus, which can be propagated in vitro in primary duck embryonic hepatocytes. The paper also describes how and why this model can be used to evaluate the efficacy of disinfectants against HBV.
Publish Date	2014-01-19 14:17
Citation	Sauerbrei A. Is hepatitis B-virucidal validation of biocides possible with the use of surrogates? World J Gastroenterol 2014; 20(2): 436-444
URL	http://www.wjgnet.com/1007-9327/full/v20/i2/436.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i2.436

Full Article (PDF)	WJG-20-436.pdf
Full Article (Word)	WJG-20-436.doc
Manuscript File	4797-Review.doc
Answering Reviewers	4797-Answering reviewers.pdf
Copyright License Agreement	4797-Copyright Assignement.pdf
Non-Native Speakers of English Editing Certificate	4797-Language certificate.pdf
Peer-review Report	4797-Peer review(s).pdf
Scientific Editor Work List	4797-Scientific editor work list.doc