Publication Name	World Journal of Critical Care Medicine
Manuscript ID	48000
Country	United States

Received	2019-04-06 07:33
Peer-Review Started	2019-04-08 06:20
To Make the First Decision	2019-08-06 01:17
Return for Revision	2019-08-06 06:06
Revised	2019-08-13 03:32
Second Decision	2019-08-21 03:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-08-21 16:49
Articles in Press	2019-08-21 16:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-09-05 06:22
Publish the Manuscript Online	2019-09-12 10:38

ISSN	2220-3141(online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Critical Care Medicine
Manuscript Type	Case Report
Article Title	Tuberculosis septic shock, an elusive pathophysiology and hurdles in management: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Rashmi Mishra, Harish Patel, Rakesh Singasani and Trupti Vakde
ORCID	Author(s) ORCID Number Rashmi Mishra http://orcid.org/0000-0001-6747-6490 Harish Patel http://orcid.org/0000-0003-3638-9495 Rakesh Singasani http://orcid.org/0000-0001-5094-7663 Trupti Vakde http://orcid.org/0000-0002-5154-3051
Funding Agency and Grant Number
Corresponding Author	Trupti Vakde, MD, Attending Doctor, Division of Pulmonary and Critical Care, Department of Medicine, Bronx Care Health System, 1650 Grand concourse, Bronx, NY 10457, United States. truptivakde@gmail.com
Key Words	Tuberculosis septic shock; Tuberculosis and immune reconstitution; Tuberculosis in intensive care unit; Case fatality for tuberculosis septic shock; Case report;
Core Tip	Tuberculosis septic shock is a rare entity. We present three cases of tuberculosis septic shock with varied clinical manifestations. Mycobacterium tuberculosis culture or nucleic acid amplification testing confirmed diagnosis of tuberculosis. All of our presented cases had poor outcome despite timely administration of appropriate anti-tuberculosis regimen. There was clinical and radiological deterioration after administration of anti-microbial agents. This deteriorating clinical course raises a concern for immune reconstitution as possible pathogenesis for tuberculosis septic shock.
Publish Date	2019-09-12 10:38
Citation	Mishra R, Patel HK, Singasani R, Vakde T. Tuberculosis septic shock, an elusive pathophysiology and hurdles in management: A series of three case report and review of literature. World J Crit Care Med 2019; 8(5): 72-81
URL	https://www.wjgnet.com/2220-3141/full/v8/i5/72.htm
DOI	https://dx.doi.org/10.5492/wjccm.v8.i5.72

Full Article (PDF)	WJCCM-8-72.pdf
Full Article (Word)	WJCCM-8-72.docx
Manuscript File	48000-Review.docx
Answering Reviewers	48000-Answering reviewers.pdf
Audio Core Tip	48000-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	48000-Conflict-of-interest statement.pdf
Copyright License Agreement	48000-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	48000-Informed consent statement.pdf
Peer-review Report	48000-Peer-review(s).pdf
Scientific Misconduct Check	48000-Scientific misconduct check.pdf
Scientific Editor Work List	48000-Scientific editor work list.pdf