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7/28/2019 10:51:57 AM | Browse: 1418 | Download: 2867
Publication Name World Journal of Gastroenterology
Manuscript ID 48037
Country China
Received
2019-04-03 05:00
Peer-Review Started
2019-04-03 06:33
First Decision by Editorial Office Director
2019-05-30 21:05
Return for Revision
2019-05-31 01:53
Revised
2019-06-04 11:26
Publication Fee Transferred
Second Decision by Editor
2019-06-17 10:23
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2019-06-23 01:55
Articles in Press
2019-06-23 01:55
Edit the Manuscript by Language Editor
2019-06-28 08:45
Typeset the Manuscript
2019-07-26 06:51
Publish the Manuscript Online
2019-07-28 10:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Effect of Low-dose aspirin administration on long-term survival of cirrhotic patients after splenectomy: A retrospective single-center study
Manuscript Source Unsolicited Manuscript
All Author List Zhao-Qing Du, Jun-Zhou Zhao, Jian Dong, Jian-Bin Bi, Yi-Fan Ren, Jia Zhang, Bilawal Khalid, Zheng Wu, Yi Lv, Xu-Feng Zhang and Rong-Qian Wu
ORCID
Author(s) ORCID Number
Zhao-Qing Du http://orcid.org/0000-0003-0781-1079
Jun-Zhou Zhao http://orcid.org/0000-0003-0365-2568
Jian Dong http://orcid.org/0000-0213-0555-6589
Jian-Bin Bi http://orcid.org/0000-0002-9281-1999
Yi-Fan Ren http://orcid.org/0000-0123-4465-2368
Jia Zhang http://orcid.org/0000-0001-7306-3350
Bilawal Khalid http://orcid.org/0000-1233-5662-2698
Zheng Wu http://orcid.org/0000-0002-7102-9543
Yi Lv http://orcid.org/0000-0002-7104-2414
Xu-Feng Zhang http://orcid.org/0000-0002-7908-1645
Rong-Qian Wu http://orcid.org/0000-0003-0993-4531
Funding Agency and Grant Number
Funding Agency Grant Number
the Ministry of Education Innovation Team Development Program of China IRT16R57
Corresponding Author Rong-Qian Wu, MD, PhD, Professor, National Local Joint Engineering Research Center for Precision Surgery and Regenerative Medicine, First Affiliated Hospital of Xi'an Jiaotong University, 76 West Yanta Road, P.O. Box 124, Xi’an 710061, Shaanxi Province, China. rwu001@mail.xjtu.edu.cn
Key Words Aspirin; Splenectomy; Prognosis; Hepatocellular carcinoma; Overall survival;
Core Tip Anticoagulant therapy reduces the incidence of postsplenectomy portal thrombosis and improves prognosis by inhibiting thrombus formation. This study was to investigate the effect of long-term low-dose postoperative aspirin on the development of hepatocellular carcinoma and long-term survival of cirrhotic patients after splenectomy. Long-term post-splenectomy administration of low-dose aspirin reduced the incidence of hepatocellular carcinoma and improved the long-term overall survival in patients with viral hepatitis-related cirrhosis. Thus, long-term low-dose aspirin therapy should be recommended to cirrhotic patients with hypersplenism after splenectomy.
Publish Date 2019-07-28 10:51
Citation Du ZQ, Zhao JZ, Dong J, Bi JB, Ren YF, Zhang J, Khalid B, Wu Z, Lv Y, Zhang XF, Wu RQ. Effect of Low-dose aspirin administration on long-term survival of cirrhotic patients after splenectomy: A retrospective single-center study. World J Gastroenterol 2019; 25(28): 3798-3807
URL https://www.wjgnet.com/1007-9327/full/v25/i28/3798.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i28.3798
Full Article (PDF) WJG-25-3798.pdf
Full Article (Word) WJG-25-3798.docx