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8/6/2019 11:50:46 AM | Browse: 409 | Download: 688
Publication Name World Journal of Clinical Cases
Manuscript ID 48038
Country China
Received
2019-04-09 01:34
Peer-Review Started
2019-04-12 06:50
To Make the First Decision
2019-06-03 03:39
Return for Revision
2019-06-11 08:22
Revised
2019-06-28 01:26
Second Decision
2019-07-02 10:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-07-03 16:54
Articles in Press
2019-07-03 16:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-07-17 20:59
Typeset the Manuscript
2019-07-28 09:34
Publish the Manuscript Online
2019-08-06 11:50
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Ophthalmology
Manuscript Type Case Control Study
Article Title Changes in corneal endothelial cell density in patients with primary open-angle glaucoma
Manuscript Source Unsolicited Manuscript
All Author List Zi-Yan Yu, Ling Wu and Bo Qu
ORCID
Author(s) ORCID Number
Zi-Yan Yu http://orcid.org/0000-0003-1091-428X
Ling Wu http://orcid.org/0000-0003-3057-6302
Bo Qu http://orcid.org/0000-0002-2261-8464
Funding Agency and Grant Number
Corresponding Author Bo Qu, MD, PhD, Associate Professor, Department of Ophthalmology, 4th affiliated hospital of China Medical University, Eye hospital of China Medical University, Key Laboratory of lens research of Liaoning Province, 11 Xinhua Road, Shenyang 110004, Liaoning Province, China. dolphinemu@foxmail.com
Key Words Corneal endothelium; Primary open angle glaucoma; Intraocular pressure; ; ;
Core Tip Loss of corneal endothelial cells have been reported in primary open-angle glaucoma (POAG) patients. Elevated intraocular pressure (IOP), cell toxicity after long-term exposure to preservatives and glaucoma surgery has been reported to be possible mechanism for endothelial damage. In this study, we aimed to document the corneal endothelial changes and their correlations with mean IOP between POAG patients and normal controls. We found that the corneal endothelial cell density in POAG patients is decreased and the average endothelial cell area is increased compared with those in healthy controls. High IOP and anti-glaucoma medication in POAG may be the main causes of corneal endothelial cell damage.
Publish Date 2019-08-06 11:50
Citation Yu ZY, Wu L, Qu B. Changes in corneal endothelial cell density in patients with primary open-angle glaucoma. World J Clin Cases 2019; 7(15):1978-1985
URL https://www.wjgnet.com/2307-8960/full/v7/i15/1978.htm
DOI https://dx.doi.org/10.12998/wjcc.v7.i15.1978
Full Article (PDF) WJCC-7-1978.pdf
Full Article (Word) WJCC-7-1978.docx
Manuscript File FP6913_de16_CE1MS_edit2 190717.docx
Answering Reviewers 48038-Answering reviewers.pdf
Audio Core Tip 48038-Audio-Core-Tip-revision.m4a
Biostatistics Review Certificate 48038-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 48038-Conflict-of-interest statement.pdf
Copyright License Agreement 48038-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 48038-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 48038-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 48038-Language certificate.pdf
Peer-review Report 48038-Peer-review(s).pdf
Scientific Misconduct Check 48038-Scientific misconduct check.pdf
Scientific Editor Work List 48038-Scientific editor work list.pdf