| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Regulatory effect of Chinese herbal medicine on non-alcoholic fatty liver disease
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jia-Min Yang, Yan Sun, Min Wang, Xin-Lei Zhang, Shu-Jing Zhang, Yu-Shan Gao, Lin Chen, Meng-Yao Wu, Lu Zhou, Yu-Mei Zhou, Yue Wang, Feng-Jie Zheng and Yu-Hang Li |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81673868 |
|
| Corresponding Author |
Yu-Hang Li, PhD, Professor, School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, No.11 Beisanhuan Donglu, Chaoyang District, Beijing 100029, China, Beijing 100029, China. liyuhang@bucm.edu.cn |
| Key Words |
Non-alcoholic fatty liver disease; Chinese herbal medicine; Liver function; Intestinal-hepatic axis; ; |
| Core Tip |
Based on the previous study about “intestinal-hepatic axis”, we hypothesized that the effect of Chinese herbal medicine (CHM) on non-alcoholic fatty liver disease by regulating the liver and intestine. In this study, we find the CHM thorowax root, scutellaria root, and white peony root had good effect on regulating lipid metabolism and liver function, which suggested its ability to regulate the liver. To a certain extent, it also had a regulatory effect on the intestinal mucosal barrier. Our study demonstrated that CHM can affect both the liver and intestine, while the effect of CHM on the liver was superior to the intestine. |
| Publish Date |
2019-09-12 08:50 |
| Citation |
Yang JM, Sun Y, Wang M, Zhang XL, Zhang SJ, Gao YS, Chen L, Wu MY, Zhou L, Zhou YM, Wang Y, Zheng FJ, Li YH. Regulatory effect of Chinese herbal medicine on non-alcoholic fatty liver disease. World J Gastroenterol 2019; 25(34): 5105-5119 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i34/5105.htm |
| DOI |
ttps://dx.doi.org/10.3748/wjg.v25.i34.5105 |
