| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Incidence of infectious complications is associated with a high mortality in patients with hepatitis B virus-related acute-on-chronic liver failure
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chen Wang, De-Qiang Ma, Sen Luo, Chuan-Min Wang, De-Ping Ding, You-You Tian, Kang-Jian Ao, Yin-Hua Zhang, Yue Chen and Zhong-Ji Meng |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Foundation for Innovative Research Groups of Natural Science Foundation of Hubei Province of China |
No. 2018CFA031 |
| Precision Medical Project Granted by National Key Research and Development Program |
No. 2017YFC0908104 |
| Research and development project of science and technology plan of Shiyan |
No. 18K78 |
| Key Program for Precision Medicine of Taihe Hospital |
No. 2016JZ05 |
|
| Corresponding Author |
Zhong-Ji Meng, MD, Chief Doctor, Full Professor, Research Scientist, Institute of Biomedical Research, Department of Infectious Diseases, Taihe Hospital, Hubei University of Medicine, South Renmin Road, No.32, Shiyan 442000, Hubei Province, China. zhongji.meng@163.com |
| Key Words |
Hepatitis B; Acute-on-chronic liver failure; Bacterial infection; Fungal infection; Prognosis; |
| Core Tip |
Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) is the most common type of liver failure with high mortality and complications. Bacterial and/or fungal infections are the most common complications of liver failure. The aim of this study was to investigate the frequency and the role of bacterial and fungal infections in patients with HBV-ACLF. 174 patients with HBV-ACLF were retrospectively analyzed. Patients with infection complications had significantly higher mortality (70.18%) than those without infection complications (40.00%, 24/60). In conclusion, infection can significantly increase the mortality rate of liver failure. |
| Publish Date |
2019-08-26 02:56 |
| Citation |
Wang C, Ma DQ, Luo S, Wang CM, Ding DP, Tian YY, Ao KJ, Zhang YH, Chen Y, Meng ZJ. Incidence of infection complication is associated with high mortality in patients with hepatitis B virus-related acute-on-chronic liver failure. World J Clin Cases 2019; 7(16): 2204-2216 |
| URL |
https://www.wjgnet.com/2307-8960/full/v7/i16/ 2204.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v7.i16.2204 |
