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Articles Published Processes
9/7/2019 4:43:36 AM | Browse: 792 | Download: 1438
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Received |
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2019-04-11 00:37 |
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Peer-Review Started |
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2019-04-11 05:34 |
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To Make the First Decision |
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2019-05-17 00:26 |
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Return for Revision |
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2019-05-24 06:44 |
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Revised |
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2019-05-31 10:10 |
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Second Decision |
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2019-06-05 10:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-06-08 14:56 |
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Articles in Press |
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2019-06-08 14:56 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-04 01:08 |
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Publish the Manuscript Online |
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2019-09-07 04:43 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Ex vivo effect of vascular wall stromal cells secretome on enteric ganglia
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Giovanni Dothel, Chiara Bernardini, Augusta Zannoni, Maria Rosaria Spirito, Roberta Salaroli, Maria Laura Bacci, Monica Forni and Fabrizio De Ponti |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fondazione del Monte di Bologna e Ravenna |
FdM/3208 |
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| Corresponding Author |
Monica Forni, PhD, Associate Professor, Professor, Department of Veterinary Medical Sciences, University of Bologna, Via Tolara di Sopra 50, Ozzano dell'Emilia, Bologna 40064, Italy. monica.forni@unibo.it |
| Key Words |
Enteric nervous system; Mesenchymal stromal cells; Inflammatory bowel disease; Ganglia; Translational models; |
| Core Tip |
Secretome of porcine vascular wall mesenchymal stromal cells (pVW-MSCs) induced an increase of glial cell number in swine and guinea pig-derived enteric ganglia. Co-treatment of enteric ganglia with lipopolysaccharide and conditioned medium promoted glial cell differentiation only in pigs. These data indicate an immune activation promoted by pVW-MSCs which could be more specific in higher mammals, suggesting a careful consideration of the animal models used in research studies on cell-based therapies. |
| Publish Date |
2019-09-07 04:43 |
| Citation |
Dothel G, Bernardini C, Zannoni A, Spirito MR, Salaroli R, Bacci ML, Forni M, De Ponti F. Ex vivo effect of vascular wall stromal cells secretome on enteric ganglia. World J Gastroenterol 2019; 25(33): 4892-4903 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i33/4892.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i33.4892 |
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