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Articles Published Processes
9/28/2019 10:12:50 AM | Browse: 887 | Download: 2091
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Received |
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2019-04-26 01:26 |
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Peer-Review Started |
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2019-04-26 03:00 |
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First Decision by Editorial Office Director |
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2019-05-24 11:30 |
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Return for Revision |
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2019-05-31 02:26 |
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Revised |
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2019-08-07 05:43 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2019-08-16 09:16 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2019-08-19 13:40 |
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Articles in Press |
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2019-08-19 13:40 |
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Edit the Manuscript by Language Editor |
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2019-09-09 22:52 |
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Typeset the Manuscript |
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2019-09-27 08:57 |
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Publish the Manuscript Online |
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2019-09-28 10:12 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
High mobility group box-1 release from H<Sub>2</Sub>O<Sub>2</Sub>-injured hepatocytes due to sirt1 functional inhibition
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ting-Jie Ye, Yan-Lin Lu, Xiao-Feng Yan, Xu-Dong Hu and Xiao-Ling Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81503367; 81703832 |
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| Corresponding Author |
Xiao-Ling Wang, MD, Full Professor, Department of Biology, School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Pudong, Shanghai 210203, China. shengwuwang12@126.com |
| Key Words |
Sirtuin1; Poly ADP-ribose polymerase 1; High mobility group box-1; Hepatocytes; Hydrogen peroxide; |
| Core Tip |
High mobility group box 1 (HMGB1) is a protein in nucleus non-specifically binds to the minor grooves in DNA. Once released passively by necrotic and damaged cells, HMGB1 will become a damage-associated molecular pattern molecule triggering the inflammatory response and ultimately results in tissue damage. In the present study, we found that HMGB1 release from H2O2-injured hepatocytes due to sirt1 functional inhibition. |
| Publish Date |
2019-09-28 10:12 |
| Citation |
Ye TJ, Lu YL, Yan XF, Hu XD, Wang XL. High mobility group box-1 release from H2O2-injured hepatocytes due to sirt1 functional inhibition. World J Gastroenterol 2019; 25(36): 5434-5450 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i36/5434.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i36.5434 |
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