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Articles Published Processes
12/31/2019 7:02:25 AM | Browse: 883 | Download: 1669
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Received |
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2019-04-15 00:35 |
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Peer-Review Started |
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2019-04-15 06:38 |
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To Make the First Decision |
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2019-05-28 03:00 |
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Return for Revision |
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2019-06-11 07:41 |
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Revised |
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2019-07-26 22:58 |
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Second Decision |
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2019-09-30 02:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-10-02 03:57 |
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Articles in Press |
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2019-10-02 03:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-12-08 03:56 |
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Typeset the Manuscript |
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2019-12-16 07:27 |
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Publish the Manuscript Online |
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2019-12-31 07:02 |
| ISSN |
1948-5204 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Abnormal CD44 activation of hepatocytes with nonalcoholic fatty accumulation in rat hepatocarcinogenesis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Miao Fang, Min Yao, Jie Yang, Wen-Jie Zheng, Li Wang and Deng-Fu Yao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
31872738 |
| National Natural Science Foundation |
81673241 |
| National Natural Science Foundation |
81702419 |
| National Natural Science Foundation of China |
81873915 |
| Ministry of S. & T. National Key Research & Development Program |
2018YFC0116902 |
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| Corresponding Author |
Deng-Fu Yao, MD, PhD, Director, Director, Professor, Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu Province, China, Nantong 226001, Jiangsu Province, China. yaodf@ahnmc.com |
| Key Words |
Hepatocarcinogenesis; CD44; Nonalcoholic fatty liver disease; Animal model; Dynamic expressions; |
| Core Tip |
CD44 belonged to a family of adhesion molecules was a marker of cancer stem cells and related to the process about NAFLD developing to NASH and HCC. Dynamic expressions of CD44 in livers or blood at protein or mRNA level were investigated at different stages of fatty accumulating liver progression. The increasing CD44 expression could be one of the most important progenitors and associated with the malignant transformation of hepatocytes with lipid accumulation. |
| Publish Date |
2019-12-31 07:02 |
| Citation |
Fang M, Yao M, Yang J, Zheng WJ, Wang L, Yao DF. Abnormal CD44 activation of hepatocytes with nonalcoholic fatty accumulation in rat hepatocarcinogenesis. World J Gastrointest Oncol 2020; 12(1): 66-76 |
| URL |
https://www.wjgnet.com/1948-5204/full/v12/i1/66.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v12.i1.66 |
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