Publication Name	World Journal of Gastroenterology
Manuscript ID	48295
Country	United States

Received	2019-04-13 06:00
Peer-Review Started	2019-04-15 06:13
To Make the First Decision	2019-05-17 00:32
Return for Revision	2019-05-24 01:03
Revised	2019-05-31 17:35
Second Decision	2019-07-09 09:21
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2019-07-19 15:58
Articles in Press	2019-07-19 15:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-08-19 06:28
Publish the Manuscript Online	2019-08-21 09:19

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright	© The Author(s) 2019 Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Methionine adenosyltransferases in liver cancer
Manuscript Source	Invited Manuscript
All Author List	Ben Murray, Lucia Barbier-Torres, Wei Fan, Jose M Mato and Shelly C Lu
ORCID	Author(s) ORCID Number Ben Murray http://orcid.org/0000-0001-5375-2124 Lucia Barbier-Torres http://orcid.org/0000-0002-7675-2888 Wei Fan http://orcid.org/0000-0001-6462-7425 Jose M Mato http://orcid.org/0000-0003-1264-3153 Shelly C Lu http://orcid.org/0000-0003-2128-5407
Funding Agency and Grant Number	Funding Agency Grant Number National Institutes of Health, NIAAA R01AA026759 National Institutes of Health, NIDDK R01DK107288 National Institutes of Health, NCCIH R01AT001576 National Institutes of Health, NCI R01CA172086 Agencia Estatal de Investigación MINECO SAF 2017-88041-R ISCiii PIE14/00031 CIBERehd-ISCiii Severo Ochoa Excellence Accreditation SEV-2016-0644
Corresponding Author	Shelly C Lu, MD, Professor, Department of Medicine, Division of Digestive and Liver Diseases, Cedars-Sinai Medical Center, 8700 Beverly Blvd., Davis Building 2097, Los Angeles, CA 90048, United States. shelly.lu@cshs.org
Key Words	Methionine adenosyltransferases; S-adenosylmethionine; Liver cancer; Hepatocellular carcinoma; Cholangiocarcinoma; Biomarkers
Core Tip	In this review we provide the most comprehensive guide to methionine adenosyltransferases discussing their structures, functions and consequences of dysregulation in liver cancers emphasizing their potential as prognostic biomarkers for liver cancers and as targets for liver cancer therapy.
Publish Date	2019-08-21 09:19
Citation	Murray B, Barbier-Torres L, Fan W, Mato JM, Lu SC. Methionine adenosyltransferases in liver cancer. World J Gastroenterol 2019; 25(31): 4300-4319
URL	https://www.wjgnet.com/1007-9327/full/v25/i31/4300.htm
DOI	https://dx.doi.org/10.3748/wjg.v25.i31.4300

Full Article (PDF)	WJG-25-4300.pdf
Full Article (Word)	WJG-25-4300.docx
Manuscript File	48295-Review.docx
Answering Reviewers	48295-Answering reviewers.pdf
Audio Core Tip	48295-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	48295-Conflict-of-interest statement.pdf
Copyright License Agreement	48295-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	48295-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	48295-Language certificate.pdf
Peer-review Report	48295-Peer-review(s).pdf
Scientific Misconduct Check	48295-Scientific misconduct check.pdf
Scientific Editor Work List	48295-Scientific editor work list.pdf
CrossCheck Report	48295-CrossCheck Report.pdf