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Articles Published Processes
8/28/2019 12:23:27 PM | Browse: 937 | Download: 1624
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Received |
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2019-04-15 00:35 |
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Peer-Review Started |
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2019-04-15 06:44 |
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To Make the First Decision |
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2019-06-17 00:40 |
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Return for Revision |
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2019-06-21 02:12 |
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Revised |
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2019-06-27 04:21 |
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Second Decision |
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2019-07-05 10:31 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-07-05 23:43 |
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Articles in Press |
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2019-07-05 23:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-07-15 04:09 |
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Typeset the Manuscript |
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2019-08-28 06:14 |
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Publish the Manuscript Online |
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2019-08-28 12:23 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Effect of mild moxibustion on intestinal microbiota and NLRP6 inflammasome signaling in rats with post-inflammatory irritable bowel syndrome
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chun-Hui Bao, Chun-Ye Wang, Guo-Na Li, Yi-Lu Yan, Di Wang, Xiao-Ming Jin, Lu-Yi Wu, Hui-Rong Liu, Xiao-Mei Wang, Zheng Shi and Huan-Gan Wu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81503656 |
| National Key Basic Research Program of China (973 program) |
2015CB554501 and 2009CB522900 |
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| Corresponding Author |
Huan-Gan Wu, PhD, Professor, Key Laboratory of Acupuncture and Immunological Effects, Shanghai University of Traditional Chinese Medicine, 650 South Wanping Road, Xuhui District, Shanghai 200030, China. wuhuangan@126.com |
| Key Words |
Moxibustion; Post-inflammation irritable bowel syndrome; Intestinal microbes; NLRP6 inflammasome; Intestinal inflammation; Visceral hypersensitivity |
| Core Tip |
Moxibustion has been shown to have a therapeutic effect on post-infectious/post-inflammatory irritable bowel syndrome (PI-IBS). However, it is unclear whether moxibustion achieves its therapeutic effect by regulating intestinal microbiota and inflammatory responses of PI-IBS. In this study, we found that visceral hypersensitivity and low-grade intestinal inflammation in PI-IBS rats were significantly inhibited by 7 d mild moxibustion treatment. This treatment effect of moxibustion may be related to the regulating the relative abundances of selected gut microbes and controlling NLRP6 inflammasome signaling. |
| Publish Date |
2019-08-28 12:23 |
| Citation |
Bao CH, Wang CY, Li GN, Yan YL, Wang D, Jin XM, Wu LY, Liu HR, Wang XM, Shi Z, Wu HG. Effect of mild moxibustion on intestinal microbiota and NLRP6 inflammasome signaling in rats with post-inflammatory irritable bowel syndrome. World J Gastroenterol 2019; 25(32): 4696-4714 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i32/4696.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i32.4696 |
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