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Articles Published Processes
9/15/2014 9:24:00 AM | Browse: 1025 | Download: 1063
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Received |
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2013-07-26 11:03 |
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Peer-Review Started |
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2013-07-26 12:09 |
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To Make the First Decision |
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2013-08-08 11:34 |
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Return for Revision |
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2013-08-08 15:56 |
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Revised |
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Second Decision |
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2013-08-29 07:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-08-29 10:03 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-10-11 00:00 |
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Publish the Manuscript Online |
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2013-12-31 17:17 |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Editorial |
Article Title |
Current status of clinical islet transplantation
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Manuscript Source |
Invited Manuscript |
All Author List |
Andrew R Pepper, Boris Gala-Lopez, Oliver Ziff and AM James Shapiro |
Funding Agency and Grant Number |
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Corresponding Author |
AM James Shapiro, MD, PhD, Professor, Director of Clinical Islet and Living Donor Liver Transplant Programs, Department of Clinical Islet Transplant Program, University of Alberta, 2000 College Plaza, 8215-112th St, Edmonton T6G 2C8, Alberta, Canada. amjs@islet.ca |
Key Words |
Islet transplantation; Type 1 diabetes; Immunosuppression |
Core Tip |
Core tip: Since the initial inception of the “Edmonton protocol”, phenomenal progress has transpired in the last decade. These milestones were namely due to the implementation of numerous pre-clinical and clinical investigations, testing innovative agents allowing potent immunotolerance with minimal complications as well as alternative transplant sites to overcome limitations inherent to the current intraportal access. As a result nearly 80% of full or partial graft function, out of more than 300 transplants performed to date. As the field of continues to work and progress together, it is foreseeable that a cure for type 1 diabetes mellitus is obtainable in the near future. |
Publish Date |
2013-12-31 17:17 |
Citation |
Pepper AR, Gala-Lopez B, Ziff O, Shapiro AMJ. Current status of clinical islet transplantation. World J Transplant 2013; 3(4): 48-53 |
URL |
http://www.wjgnet.com/2220-3230/full/v3/i4/48.htm |
DOI |
http://dx.doi.org/10.5500/wjt.v3.i4.48 |
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