Publication Name	World Journal of Stem Cells
Manuscript ID	4840
Country	United States

Received	2013-07-26 11:21
Peer-Review Started	2013-07-26 13:28
To Make the First Decision	2013-08-21 18:37
Return for Revision	2013-08-22 19:27
Revised	2013-09-06 07:22
Second Decision	2013-09-16 13:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-09-17 05:35
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-21 08:24
Publish the Manuscript Online	2013-10-31 14:50

ISSN	1948-0210 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Biology
Manuscript Type	Editorial
Article Title	Advances in homology directed genetic engineering of human pluripotent and adult stem cells
Manuscript Source	Invited Manuscript
All Author List	Kalpith Ramamoorthi, Donald Curtis and Prashanth Asuri
Funding Agency and Grant Number
Corresponding Author	Prashanth Asuri, PhD, Department of Bioengineering, Santa Clara University, 500 El Camino Real, Santa Clara, CA 95053, United States. asurip@scu.edu
Key Words	Human stem cells; Genetic engineering; Engineered viruses; Synthetic restriction endonucleases
Core Tip	This manuscript focuses on the development of novel technologies to precisely alter the human stem cell genome and highlights their implications for both basic and applied stem cell research. Specifically, we discuss the development of two main technologies: molecular engineering of viral vectors and design of artificial endonucleases. We also discuss the merits of combining these complementary approaches and suggest other possible strategies that could be explored to further improve genetic engineering of human stem cells.
Publish Date	2013-10-31 14:50
Citation	Ramamoorthi K, Curtis D, Asuri P. Advances in homology directed genetic engineering of human pluripotent and adult stem cells. World J Stem Cells 2013; 5(4): 98-105
URL	http://www.wjgnet.com/1948-0210/full/v5/i4/98.htm
DOI	http://dx.doi.org/10.4252/wjsc.v5.i4.98

Full Article (PDF)	WJSC-5-98.pdf
Manuscript File	4840-Review.doc
Answering Reviewers	4840-Answering reviewers.pdf
Copyright License Agreement	4840-Copyright Assignment.pdf
Peer-review Report	4840-Peer review(s).pdf
Scientific Editor Work List	4840-Scientific editor work list.doc