Publication Name	World Journal of Gastroenterology
Manuscript ID	48495
Country	China

Received	2019-04-22 00:57
Peer-Review Started	2019-04-22 05:50
To Make the First Decision	2019-06-10 07:58
Return for Revision	2019-06-11 01:04
Revised	2019-07-18 06:55
Second Decision	2019-08-02 10:12
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2019-08-07 09:38
Articles in Press	2019-08-07 09:38
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-08-14 04:16
Typeset the Manuscript	2019-09-17 01:25
Publish the Manuscript Online	2019-09-21 07:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Significance of tumor-infiltrating immunocytes for predicting the prognosis of hepatitis B virus-related hepatocellular carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Qi-Feng Chen, Wang Li, Pei-Hong Wu, Lu-Jun Shen and Zi-Lin Huang
ORCID	Author(s) ORCID Number Qi-Feng Chen http://orcid.org/0000-0001-8998-3450 Wang Li http://orcid.org/0000-0002-4293-8182 Pei-Hong Wu http://orcid.org/0000-0001-8008-1872 Lu-Jun Shen http://orcid.org/0000-0002-7936-0206 Zi-Lin Huang http://orcid.org/0000-0002-1643-1994
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81801804
Corresponding Author	Zi-Lin Huang, MD, Professor, Medical Imaging and Interventional Radiology, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Yuexiu District, Guangzhou 510060, Guangdong Province, China. huangzl@sysucc.org.cn
Key Words	Immune risk score; Hepatitis B virus; Hepatocellular carcinoma; Prognostic signature; Cell type identification by estimating relative subsets of RNA transcripts;
Core Tip	Hepatitis B virus (HBV) infection is epidemiologically related to hepatocellular carcinoma (HCC) development. Immune cells have been recognized to play crucial roles in the prognosis of various types of cancers, including HCC. The immune signature for HBV-related HCC remains unknown. In this study, we explored the proportions of immunocytes, and constructed a robust immune signature to predict the prognosis. These results might contribute to risk stratification and facilitate individualized clinical approach for HBV-related HCC.
Publish Date	2019-09-21 07:11
Citation	Chen QF, Li W, Wu PH, Shen LJ, and Huang ZL. Significance of tumor-infiltrating immunocytes for predicting the prognosis of hepatitis B virus-related hepatocellular carcinoma. World J Gastroenterol 2019; 25(35): 5266-5282
URL	https://www.wjgnet.com/1007-9327/full/v25/i35/5266.htm
DOI	https://dx.doi.org/10.3748/wjg.v25.i35.5266

Full Article (PDF)	WJG-25-5266.pdf
Full Article (Word)	WJG-25-5266.docx
Manuscript File	48495-Review_Edited.docx
Answering Reviewers	48495-Answering reviewers.pdf
Audio Core Tip	48495-Audio core tip.mp3
Biostatistics Review Certificate	48495-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	48495-Conflict-of-interest statement.pdf
Copyright License Agreement	48495-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	48495-Language certificate.pdf
Supplementary Material	48495-Supplementary material.pdf
Peer-review Report	48495-Peer-review(s).pdf
Scientific Misconduct Check	48495-Bing-TANG JZ-2.png
Scientific Misconduct Check	48495-Scientific misconduct check.pdf
Scientific Editor Work List	48495-Scientific editor work list.pdf
CrossCheck Report	48495-CrossCheck report.pdf