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Articles Published Processes
10/16/2019 12:17:24 PM | Browse: 1064 | Download: 2197
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Received |
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2019-04-23 00:30 |
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Peer-Review Started |
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2019-05-07 00:43 |
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First Decision by Editorial Office Director |
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2019-06-04 16:31 |
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Return for Revision |
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2019-06-12 01:44 |
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Revised |
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2019-06-19 13:17 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2019-07-26 11:05 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2019-07-28 17:50 |
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Articles in Press |
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2019-07-28 17:50 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-10 08:53 |
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Publish the Manuscript Online |
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2019-10-16 12:17 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
MicroRNA-320a suppresses tumor progression by targeting PBX3 in gastric cancer and is downregulated by DNA methylation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yong-Shuang Li, Ying Zou and Dong-Qiu Dai |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Liaoning Province |
201602817 |
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| Corresponding Author |
Dong-Qiu Dai, MD, PhD, Chief Physician, Professor, Department of Gastrointestinal Surgery, the Fourth Affiliated Hospital of China Medical University, No. 4 Chongshan East Road, Shenyang 110032, Liaoning Province, China. daidq63@163.com |
| Key Words |
Gastric cancer; miR-320a; DNA methylation; PBX3; tumor suppressor; |
| Core Tip |
miR-320a functioned as a tumor suppressor and was downregulated in gastric cancer. miR-320a overexpressionsuppressed proliferation, migration, invasion, while induced apoptosis through targeting PBX3 in GC cells. miR-320a depletion showed the opposite results. The potential mechanism of miR-320a deficiency in gastric cancer was that methylation level of the miR-320a promoter CpG islands was elevated. |
| Publish Date |
2019-10-16 12:17 |
| Citation |
Li YS, Zou Y, Dai DQ. MicroRNA-320a suppresses tumor progression by targeting PBX3 in gastric cancer and is downregulated by DNA methylation. World J Gastrointest Oncol 2019; 11(10): 842-856 |
| URL |
https://www.wjgnet.com/1948-5204/full/v11/i10/842.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v11.i10.842 |
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