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11/15/2019 7:45:48 AM | Browse: 588 | Download: 1067
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 48710
Country China
Received
2019-04-29 01:30
Peer-Review Started
2019-05-09 03:04
To Make the First Decision
2019-08-01 00:23
Return for Revision
2019-08-01 06:48
Revised
2019-08-10 13:43
Second Decision
2019-09-10 10:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-09-10 23:15
Articles in Press
2019-09-10 23:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-09-26 01:34
Typeset the Manuscript
2019-10-23 01:15
Publish the Manuscript Online
2019-11-15 07:45
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Observational Study
Article Title Clinical significance of MLH1/MSH2 for stage II and III sporadic colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Shui-Ming Wang, Bin Jiang, You-Ping Deng, Shu-Liang Huang, Ming-Zhi Fang and Yu Wang
ORCID
Author(s) ORCID Number
Shui-Ming Wang http://orcid.org/0000-0003-0139-1843
Bin Jiang http://orcid.org/0000-0002-4622-9703
You-Ping Deng http://orcid.org/0000-0002-5951-8213
Shu-Liang Huang http://orcid.org/0000-0002-2760-0802
Ming-Zhi Fang http://orcid.org/0000-0002-6548-0549
Yu Wang http://orcid.org/0000-0002-8003-9268
Funding Agency and Grant Number
Funding Agency Grant Number
Medical Science and technology development Foundation,Nanjing Department of Health, No. YKK14140
Medical Science and technology development Foundation,Nanjing Department of Health, No. ZKX15040
Project of Administration of Traditional Chinese medicine of Jiangsu Province of China, No. LZ11101
Corresponding Author Yu Wang, MD, PhD, Chief Doctor, oncology, entern, Nanjing hospital of Chinese medicine, Nanjing 210001, Jiangsu Province, China. christinewangyu@outlook.com
Key Words Colorectal cancer; Mismatch repair gene; MLH1; MSH2; Microsatellite instability;
Core Tip Mutation or methylation of mismatch repair gene leads to microsatellite instability (MSI), which is one of the most important mechanisms of colorectal cancer (CRC). The purpose of this study was to collect data of MLH1/MSH2 and MSI status in stage II-III CRC and to assess the predictive and prognostic value of this analysis. This is the first large study in China to evaluate the role of MLH1/MSH2 in CRC and its relationship with adjuvant chemotherapy.
Publish Date 2019-11-15 07:45
Citation Wang SM, Jiang B, Deng YP, Huang SL, Fang MZ, Wang Y. Clinical significance of MLH1/MSH2 for stage II and III sporadic colorectal cancer. World J Gastrointest Oncol 2019; 11(11): 1065-1080
URL https://www.wjgnet.com/1948-5204/full/v11/i11/1065.htm
DOI https://dx.doi.org/10.4251/wjgo.v11.i11.1065
Full Article (PDF) WJGO-11-1065.pdf
Full Article (Word) WJGO-11-1065.docx
STROBE Statement 48710-STROBE-Statement-revision_4620.pdf
Manuscript File 48710-Review_Edited.docx
Answering Reviewers 48710-Answering reviewers.pdf
Audio Core Tip 48710-Audio core tip.mp3
Biostatistics Review Certificate 48710-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 48710-Conflict-of-interest statement.pdf
Copyright License Agreement 48710-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 48710-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 48710-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 48710-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 48710-Language certificate.pdf
Peer-review Report 48710-Peer-review(s).pdf
Scientific Misconduct Check 48710-Scientific misconduct check.pdf
Scientific Editor Work List 48710-Scientific editor work list.pdf