Publication Name	World Journal of Stem Cells
Manuscript ID	48747
Country	China

Received	2019-05-05 01:53
Peer-Review Started	2019-05-08 02:35
To Make the First Decision	2019-08-06 02:53
Return for Revision	2019-08-08 01:49
Revised	2019-08-12 13:34
Second Decision	2019-09-10 10:24
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2019-09-11 18:44
Articles in Press	2019-09-11 18:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-09-24 09:30
Publish the Manuscript Online	2019-10-22 07:13

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Editorial
Article Title	Applications of single cell RNA sequencing to research of stem cells
Manuscript Source	Invited Manuscript
All Author List	Xiao Zhang and Lei Liu
ORCID	Author(s) ORCID Number Xiao Zhang http://orcid.org/0000-0003-1687-0644 Lei Liu http://orcid.org/0000-0001-5309-1979
Funding Agency and Grant Number	Funding Agency Grant Number the National Natural Science Foundation of China 81670951
Corresponding Author	Lei Liu, MD, PhD, Doctor, Doctor, Professor, State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, NO.14, 3rd Section of Ren Min Nan Rd, Chengdu 610041, Sichuan Province, China. drliulei@163.com
Key Words	Stem cells; Heterogeneity; Single cell RNA sequencing; Developmental trajectories; Cell subpopulations;
Core Tip	Single cell RNA sequencing (scRNA-seq) has emerged as a powerful tool to explore cellular heterogeneity, provide new insights based on gene expression profiles of individual cells, reveal new cell subpopulations and predict developmental trajectories. It has been used in research of stem cells (SCs) in many fields, especially the study of heterogeneity and cell subpopulations in early embryonic development. This review aims to provide an overview of the applications of scRNA-seq to research of SCs.
Publish Date	2019-10-22 07:13
Citation	Zhang X, Liu L. Applications of single cell RNA sequencing to research of stem cells. World J Stem Cells 2019; 11(10):722-728
URL	https://www.wjgnet.com/1948-0210/full/v11/i10/722.htm
DOI	https://dx.doi.org/10.4252/wjsc.v11.i10.722

Full Article (PDF)	WJSC-11-722.pdf
Full Article (Word)	WJSC-11-722.docx
Manuscript File	48747-Review.docx
Answering Reviewers	48747-Answering reviewers.pdf
Audio Core Tip	48747-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	48747-Conflict-of-interest statement.pdf
Copyright License Agreement	48747-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	48747-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	48747-Language certificate.pdf
Peer-review Report	48747-Peer-review(s).pdf
Scientific Misconduct Check	48747-Scientific misconduct check.pdf
Scientific Editor Work List	48747-Scientific editor work list.pdf
CrossCheck Report	48747-CrossCheck report.pdf