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Articles Published Processes
9/7/2019 4:43:36 AM | Browse: 938 | Download: 1370
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Received |
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2019-05-09 02:27 |
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Peer-Review Started |
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2019-05-10 03:17 |
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To Make the First Decision |
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2019-07-22 02:18 |
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Return for Revision |
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2019-07-22 06:26 |
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Revised |
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2019-07-28 21:52 |
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Second Decision |
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2019-08-02 10:14 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-08-07 09:37 |
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Articles in Press |
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2019-08-07 09:37 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-04 03:23 |
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Publish the Manuscript Online |
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2019-09-07 04:43 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Minireviews |
Article Title |
Neoadjuvant radiotherapy for rectal cancer management
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Manuscript Source |
Invited Manuscript |
All Author List |
Gerard Feeney, Rishabh Sehgal, Margaret Sheehan, Aisling Hogan, Mark Regan, Myles Joyce and Michael Kerin |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
NBCRI, Symptomatic Breast Unit, University Hospital Galway |
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Corresponding Author |
Gerard Feeney, MBChB, Doctor, Doctor, Department of General/Colorectal Surgery, Lambe Institute, Galway University Hospital, Newcastle Road, Galway H91 YR71, Ireland. g.feeney3@nuigalway.ie |
Key Words |
Rectal cancer; Neoadjuvant therapy; Low anterior resection syndrome; Stoma; Transanal endoscopic microsurgery; Trans-anal total mesorectal excision |
Core Tip |
Neoadjuvant radiotherapy aims to downstage tumours for a more effective oncological resection. Studies have shown that both long and short course pre-operative radiotherapy confers benefits to local recurrence. Some patients completely respond to radiotherapy and have been enrolled in surveillance programmes without undergoing surgery. It is essential to be aware of the disadvantages associated with radiotherapy. Radiation therapy increases the risk of anorectal and genitourinary dysfunction which have a deleterious impact on quality of life. Thus it is imperative to accurately identify patients who are likely to benefit from neoadjuvant radiotherapy in order to minimise morbidity and improve patient outcomes. |
Publish Date |
2019-09-07 04:43 |
Citation |
Feeney G, Sehgal R, Sheehan M, Hogan A, Regan M, Joyce M, Kerin M. Neoadjuvant radiotherapy for rectal cancer management. World J Gastroenterol 2019;25(33): 4850-4869 |
URL |
https://www.wjgnet.com/1007-9327/full/v25/i33/4850.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v25.i33.4850 |
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