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10/25/2019 8:04:09 AM | Browse: 118 | Download: 127
Publication Name World Journal of Nephrology
Manuscript ID 48822
Country/Territory Netherlands
Received
2019-05-22 01:21
Peer-Review Started
2019-05-23 11:22
To Make the First Decision
2019-08-06 01:28
Return for Revision
2019-08-06 05:08
Revised
2019-08-29 14:13
Second Decision
2019-10-18 08:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-10-18 23:08
Articles in Press
2019-10-18 23:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-10-25 03:31
Publish the Manuscript Online
2019-10-25 08:04
ISSN 2220-6124 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology and Nephrology
Manuscript Type Case Control Study
Article Title Complement activation and long-term graft function in ABO-incompatible kidney transplantation
Manuscript Source Unsolicited Manuscript
All Author List Marit S van Sandwijk, Astrid Klooster, Ineke JM ten Berge, Arjan Diepstra, Sandrine Florquin, Joris J Hoelbeek, Frederike J Bemelman and Jan-Stephan Sanders
ORCID
Author(s) ORCID Number
Marit S van Sandwijk http://orcid.org/0000-0002-7818-6656
Astrid Klooster http://orcid.org/0000-0003-2867-5096
Ineke JM ten Berge http://orcid.org/0000-0001-8535-2766
Arjan Diepstra http://orcid.org/0000-0001-9239-1050
Sandrine Florquin http://orcid.org/0000-0002-9676-1722
Joris J Hoelbeek http://orcid.org/0000-0003-1445-4030
Frederike J Bemelman http://orcid.org/0000-0002-4454-6270
Jan-Stephan Sanders http://orcid.org/0000-0002-0904-3969
Funding Agency and Grant Number
Corresponding author Marit S van Sandwijk, MD, Staff Physician, Internist-Nephrologist, Department of Nephrology, Amsterdam University Medical Centers, location AMC, Meibergdreef 9, Amsterdam NL-1105 AZ, Netherlands. m.s.vansandwijk@amsterdamumc.nl
Keywords ABO-incompatible; Kidney transplantation; Complement; Graft function; Rejection;
Core Tip This retrospective case-control study was designed to unravel the relationship between complement activation, pre-transplant anti-ABO antibodies, and renal graft function. In this study, the slope of kidney function during a five-year follow up was not significantly different compared to matched ABO-compatible transplant recipients, but ABO-incompatible kidney transplant recipients did have a lower kidney function at three months, due to a high rate of early T-cell mediated rejection. Based on several complement staining results, we argue that this may be due to co-stimulation of T-cell activation by ongoing complement activation by anti-ABO antibodies.
Publish Date 2019-10-25 08:04
Citation van Sandwijk MS, Klooster A, ten Berge IJM, Diepstra A, Florquin S, Hoelbeek JJ, Bemelman FJ, Sanders JS. Complement activation and long-term graft function in ABO-incompatible kidney transplantation. World J Nephrol 2019; 8(6): 95-108
Url https://www.wjgnet.com/2220-6124/full/v8/i6/95.htm
DOI https://dx.doi.org/10.5527/wjn.v8.i6.95
Full Article (PDF) WJN-8-95.pdf
Full Article (Word) WJN-8-95.docx
Manuscript File 48822-Review.docx
Answering Reviewers 48822-Answering reviewers.pdf
Audio Core Tip 48822-Audio core tip.MP3
Biostatistics Review Certificate 48822-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 48822-Conflict-of-interest statement.pdf
Copyright License Agreement 48822-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 48822-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 48822-Language certificate.pdf
Peer-review Report 48822-Peer-review(s).pdf
Scientific Misconduct Check 48822-Scientific misconduct check.pdf
Scientific Editor Work List 48822-Scientific editor work list.pdf