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Articles Published Processes
9/12/2019 10:38:02 AM | Browse: 748 | Download: 1317
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Received |
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2019-05-16 01:40 |
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Peer-Review Started |
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2019-05-21 01:06 |
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To Make the First Decision |
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2019-08-01 00:21 |
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Return for Revision |
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2019-08-01 03:27 |
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Revised |
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2019-08-06 05:47 |
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Second Decision |
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2019-08-23 09:31 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-08-28 00:57 |
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Articles in Press |
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2019-08-28 00:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-06 05:46 |
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Publish the Manuscript Online |
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2019-09-12 10:38 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Case Report |
| Article Title |
Gallbladder cancer harboring ERBB2 mutation on the primary and metastatic site: A case report
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Chiaki Inagaki, Daichi Maeda, Akie Kimura, Toru Otsuru, Yoshifumi Iwagami, Naohiro Nishida, Daisuke Sakai, Ryo Shirotsuki, Shinichi Yachida, Yuichiro Doki and Taroh Satoh |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Taroh Satoh, MD, PhD, Doctor, Doctor, Professor, Department of Frontier Science for Cancer and Chemotherapy, Osaka University Graduate School of Medicine, E21-19, 2-2 Yamadaoka, Suita 5650871, Osaka, Japan. taroh@cfs.med.osaka-u.ac.jp |
| Key Words |
Gall bladder cancer; Bile duct cancer; ERBB2 mutation; Precision medicine; Mutation-driven targeted treatment; Case report |
| Core Tip |
We present a case report of a patient with GBC harboring ERBB2 hotspot extracellular domain mutation (Ser310Phe) on both primary site and the metachronous liver metastasis. Given that pathological differentiation between hepatic metastasis and primary cancer of the liver is often difficult, NGS panel could be a novel option for patients who need to distinguish a metastatic lesion from a second malignancy, which would impact on staging and the treatment strategy. This case also illustrated the benefit of HER2-targeted agent in the treatment of GBC harboring ERBB2 activating mutation. |
| Publish Date |
2019-09-12 10:38 |
| Citation |
Inagaki C, Maeda D, Kimura A, Otsuru T, Iwagami Y, Nishida N, Sakai D, Shitotsuki R, Yachida S, Doki Y, Satoh T. Gallbladder cancer harboring ERBB2 mutation on the primary and metastatic site: A case report. World J Gastrointest Oncol 2019; 11(9): 761-767 |
| URL |
https://www.wjgnet.com/1948-5204/full/v11/i9/761.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v11.i9.761 |
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