Publication Name	World Journal of Gastroenterology
Manuscript ID	4917
Country	United States

Received	2013-08-01 11:30
Peer-Review Started	2013-08-01 21:46
To Make the First Decision	2013-08-08 11:18
Return for Revision	2013-08-20 20:39
Revised	2013-09-04 04:16
Second Decision	2013-10-21 17:27
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-10-22 07:01
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-15 03:30
Typeset the Manuscript	2014-03-28 10:46
Publish the Manuscript Online	2014-04-17 13:27

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Case-control study of factors that trigger inflammatory bowel disease flares
Manuscript Source	Invited Manuscript
All Author List	Linda A Feagins, Ramiz Iqbal and Stuart J Spechler
Funding Agency and Grant Number	Funding Agency Grant Number Office of Medical Research, Department of Veteran’s Affairs, and in part, by Janssen, Inc.
Corresponding Author	Linda A Feagins, MD, Division of Gastroenterology, University of Texas Southwestern Medical Center, Dallas VA Medical Center, 4500 S Lancaster Road, Dallas, TX 75216, United States. linda.feagins@va.gov
Key Words	Inflammatory bowel diseases; Flare; Non-adherence; Crohn’s disease; Ulcerative colitis
Core Tip	Flares of Crohn’s disease and colitis are often unpredictable and physicians and patients alike search for triggers for these flares in an attempt to prevent future flares. In this study, we prospectively enrolled and queried patients with flares of inflammatory bowel diseases (IBD) and compared their responses to IBD patients in remission. We found that medication non-adherence was the only significant trigger for flares of IBD, while nonsteroidal anti-inflammatory drug use, antibiotic use, infections, smoking, travel and emotional stress were not associated with flares. Clinicians should be aware the significant role that non-adherence plays in flare-ups of IBD in order to counsel their patients appropriately.
Publish Date	2014-04-17 13:27
Citation	Feagins LA, Iqbal R, Spechler SJ. Case-control study of factors that trigger inflammatory bowel disease flares. World J Gastroenterol 2014; 20(15): 4329-4334
URL	http://www.wjgnet.com/1007-9327/full/v20/i15/4329.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i15.4329

Full Article (PDF)	WJG-20-4329.pdf
Full Article (Word)	WJG-20-4329.doc
Manuscript File	4917-Review.doc
Answering Reviewers	4917-Answering reviewers.pdf
Copyright License Agreement	4917-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20130801024202.pdf
Peer-review Report	4917-Peer reviewer(s).pdf
Scientific Editor Work List	4917-Scientific editor work list.doc