Publication Name	World Journal of Clinical Cases
Manuscript ID	49215
Country	Italy

Received	2019-05-18 05:21
Peer-Review Started	2019-05-23 00:53
To Make the First Decision	2019-08-02 02:57
Return for Revision	2019-08-06 03:02
Revised	2019-09-16 15:10
Second Decision	2019-10-14 09:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-10-15 05:21
Articles in Press	2019-10-15 05:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-11-21 11:57
Publish the Manuscript Online	2019-11-26 07:21

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Medicine, Research & Experimental
Manuscript Type	Case Report
Article Title	Cystic fibrosis transmembrane conductance regulator functional evaluations in a G542X+/- IVS8Tn:T7/9 patient with acute recurrent pancreatitis
Manuscript Source	Unsolicited Manuscript
All Author List	Sara Caldrer, Gabriella Bergamini, Angela Sandri, Silvia Vercellone, Luca Rodella, Angelo Cerofolini, Francesco Tomba, Filippo Catalano, Luca Frulloni, Mario Buffelli, Gloria Tridello, Hugo De Jonge, Baroukh Maurice Assael, Claudio Sorio and Paola Melotti
ORCID	Author(s) ORCID Number Sara Caldrer http://orcid.org/0000-0002-2379-1082 Gabriella Bergamini http://orcid.org/0000-0002-3426-9935 Angela Sandri http://orcid.org/0000-0002-5107-0960 Silvia Vercellone http://orcid.org/0000-0002-5671-733X Luca Rodella http://orcid.org/0000-0002-2355-8272 Angelo Cerofolini http://orcid.org/0000-0003-3488-5081 Francesco Tomba http://orcid.org/0000-0001-7399-2723 Filippo Catalano http://orcid.org/0000-0003-3896-9733 Luca Frulloni http://orcid.org/0000-0001-7417-2655 Mario Buffelli http://orcid.org/0000-0002-3709-013X Gloria Tridello http://orcid.org/0000-0001-7963-0977 Hugo De Jonge http://orcid.org/0000-0001-7596-7433 Baroukh Maurice Assael http://orcid.org/0000-0002-2758-7062 Claudio Sorio http://orcid.org/0000-0003-2739-4014 Paola Melotti http://orcid.org/0000-0002-5276-1595
Funding Agency and Grant Number	Funding Agency Grant Number Delegazione FFC di Palermo e di Vittoria Ragusa Catania 2 4/2013 Delegazione FFC di Treviso Montebelluna La Bottega delle Donne 3/2014 Delegazione FFC di Belluno 7/2016 Delegazione FFC di Taranto Massafra, Cosenza sud, della Valpolicella, Guadagnin SRL 6/2018 Delegazione FFC di Tradate Gallarate 13/2018 CFFT-USA ASSAEL08A0 Lega Italiana Fibrosi Cistica-Associazione Veneta ONLUS
Corresponding Author	Paola Melotti, MD, PhD, Chief Doctor, Cystic Fibrosis Center, Azienda Ospedaliera Universitaria Integrata Verona, Piazzale Stefani, 1, Verona 37126, Italy. paola.melotti@aovr.veneto.it
Key Words	Recurrent acute pancreatitis; Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator function; Intestinal current; Organoids; Sweat test
Core Tip	When the diagnosis of "idiopathic" recurrent acute pancreatitis is given, non-classical cystic fibrosis or disorders related to mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene are sometimes suspected when the phenotype is consistent with cystic fibrosis. Combination of innovative CFTR functional assays might support a controversial diagnosis, contributing to better definitions of these clinical entities.
Publish Date	2019-11-26 07:21
Citation	Caldrer S, Bergamini G, Sandri A, Vercellone S, Rodella L, Cerofolini A, Tomba F, Catalano F, Frulloni L, Buffelli M, Tridello G, de Jonge H, Assael BM, Sorio C, Melotti P. Cystic fibrosis transmembrane conductance regulator functional evaluations in a G542X+/- IVS8Tn:T7/9 patient with acute recurrent pancreatitis. World J Clin Cases 2019; 7(22): 3757-3764
URL	https://www.wjgnet.com/2307-8960/full/v7/i22/3757.htm
DOI	https://dx.doi.org/10.12998/wjcc.v7.i22.3757

Full Article (PDF)	WJCC-7-3757.pdf
Full Article (Word)	WJCC-7-3757.docx
Manuscript File	49215-Review.docx
Answering Reviewers	49215-Answering reviewers.pdf
Audio Core Tip	49215-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	49215-Conflict-of-interest statement.pdf
Copyright License Agreement	49215-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	49215-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	49215-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	49215-Language certificate.pdf
Peer-review Report	49215-Peer-review(s).pdf
Scientific Misconduct Check	49215-Scientific misconduct check.pdf
Scientific Editor Work List	49215-Scientific editor work list.pdf