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Articles Published Processes
9/21/2019 7:11:41 AM | Browse: 626 | Download: 990
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Received |
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2019-05-24 06:06 |
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Peer-Review Started |
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2019-05-27 06:35 |
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To Make the First Decision |
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2019-07-22 02:23 |
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Return for Revision |
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2019-07-23 06:47 |
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Revised |
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2019-07-30 09:57 |
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Second Decision |
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2019-08-02 10:21 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-08-07 09:34 |
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Articles in Press |
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2019-08-07 09:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-08-14 03:05 |
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Typeset the Manuscript |
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2019-09-18 08:17 |
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Publish the Manuscript Online |
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2019-09-21 07:11 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
LncRNA-ATB promotes autophagy by activating yes-associated protein and inducing autophagy-related protein 5 expression in hepatocellular carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chuan-Zhuo Wang, Guang-Xin Yan, De-Shuo Dong, He Xin and Zhao-Yu Liu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Zhao-Yu Liu, MD, Academic Research, Adjunct Professor, Chairman, Department of Radiology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang City, Liaoning Province, China: 110004, Shenyang 110004, Liaoning, China. liuzy_sj@126.com |
| Key Words |
LncRNA-ATB; Autophagy; Yes-associated protein; Autophagy-related protein 5; Hepatocellular carcinoma; |
| Core Tip |
In the present study, we identified relationship between lncRNA-activated by transforming growth factor beta (lncRNA-ATB) and autophagy in hepatocellular carcinoma (HCC). We demonstrate that lncRNA-ATB promotes autophagic flux in HCC cells. To explore the mechanism, we found that lncRNA-ATB regulates autophagy by activating yes-associated protein and increasing autophagy-related protein 5 expression. Our findings provide a novel link between lncRNA-ATB and autophagy, and suggest that lncRNA-ATB may be a potential therapeutic target in the treatment of HCC. |
| Publish Date |
2019-09-21 07:11 |
| Citation |
Wang CZ, Yan GX, Dong DS, Xin H, Liu ZY, LncRNA-ATB promotes autophagy by activating yes-associated protein and inducing autophagy-related protein 5 expression in hepatocellular carcinoma. World J Gastroenterol 2019; 25(35):5310-5322 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i35/5310.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i35.5310 |
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