Publication Name	World Journal of Stem Cells
Manuscript ID	49711
Country	China

Received	2019-06-11 00:52
Peer-Review Started	2019-06-19 09:38
To Make the First Decision	2019-08-06 02:52
Return for Revision	2019-08-06 09:26
Revised	2019-08-11 04:10
Second Decision	2019-09-04 05:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2019-09-11 17:51
Articles in Press	2019-09-11 17:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-10-17 12:29
Publish the Manuscript Online	2019-10-22 07:13

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Review
Article Title	Neural stem cell transplantation therapy for brain ischemic stroke: Review and perspectives
Manuscript Source	Invited Manuscript
All Author List	Gui-Long Zhang, Zhi-Han Zhu and Ye-Zhong Wang
ORCID	Author(s) ORCID Number Gui-Long Zhang http://orcid.org/0000-0001-5367-1535 Zhi-Han Zhu http://orcid.org/0000-0002-3917-5049 Ye-Zhong Wang http://orcid.org/0000-0002-1664-5765
Funding Agency and Grant Number	Funding Agency Grant Number China Postdoctoral Science Foundation 2019TQ0071
Corresponding Author	Ye-Zhong Wang, MD, PhD, Chairman, Chief Doctor, Professor, Department of Neurosurgery, The Second Affiliated Hospital of Guangzhou Medical University, 250 Changgang, Haizhu District,, Guangzhou 510260, Guangdong Province, China. wangyezhong@gzhmu.edu.cn
Key Words	Ischemic stroke; Neural stem cells; Transplantation; Cytokines; Exosomes;
Core Tip	In this review we compiled the latest available research regarding the use of neural stem cell therapy for the treatment of brain ischemic stroke. We discussed the benefits and limitations of this type of therapy focusing on the current efforts to improve its safety and efficacy. Further, we described a novel and clinically relevant strategy for the treatment of ischemic stroke based on cell free treatment–exosomes.
Publish Date	2019-10-22 07:13
Citation	Zhang GL, Zhu ZH, Wang YZ. Neural stem cell transplantation therapy for brain ischemic stroke: Review and perspectives. World J Stem Cells 2019; 11(10):817-830
URL	https://www.wjgnet.com/1948-0210/full/v11/i10/817.htm
DOI	https://dx.doi.org/10.4252/wjsc.v11.i10.817

Full Article (PDF)	WJSC-11-817.pdf
Full Article (Word)	WJSC-11-817.docx
Manuscript File	49711-Review.docx
Answering Reviewers	49711-Answering reviewers.pdf
Audio Core Tip	49711-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	49711-Review.docx
Copyright License Agreement	49711-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	49711-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	49711-Language certificate.pdf
Peer-review Report	49711-Peer-review(s).pdf
Scientific Misconduct Check	49711-Scientific misconduct check.pdf
Scientific Editor Work List	49711-Scientific editor work list.pdf
CrossCheck Report	49711-CrossCheck report.pdf