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Articles Published Processes
10/28/2019 11:23:12 AM | Browse: 981 | Download: 2125
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Received |
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2019-06-17 00:34 |
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Peer-Review Started |
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2019-06-17 04:02 |
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To Make the First Decision |
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2019-07-22 03:27 |
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Return for Revision |
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2019-07-23 03:40 |
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Revised |
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2019-08-09 06:19 |
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Second Decision |
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2019-09-06 12:13 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-09-09 06:00 |
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Articles in Press |
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2019-09-09 06:00 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-10-25 09:29 |
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Publish the Manuscript Online |
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2019-10-28 11:23 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Sustained virologic response to direct-acting antiviral agents predicts better outcomes in hepatitis C virus-infected patients: A retrospective study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
GianLuca Colussi, Debora Donnini, Rosario F Brizzi, Silvia Maier, Luca Valenti, Cristiana Catena, Alessandro Cavarape, Leonardo A Sechi and Giorgio Soardo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Giorgio Soardo, MD, Associate Professor, Department of Medicine, University of Udine, 1st floor, Building n.8, Piazzale Santa Maria della Misericordia 1, Udine 33100, Italy. giorgio.soardo@asuiud.sanita.fvg.it |
| Key Words |
Direct-acting antiviral agents; Hepatitis C virus; Mixed cryoglobulinemia; Sustained virologic response; Cirrhosis; Survival analysis |
| Core Tip |
The protective role of a sustained virologic response (SVR) achieved by direct-acting antiviral agents (DAAs) against the chronic consequences of hepatitis C virus (HCV) infection is not well established. We examined the occurrence of hepatocellular carcinoma (HCC) or death from any cause in a retrospective-prospective study at our tertiary academic hospital center for liver disease management. We confirmed that DAA treatment is very effective in inducing SVR in HCV-infected patients and in protecting patients against HCC development or death. However, a residual risk of HCC persists, particularly in patients with advanced liver disease or with extra-hepatic HCV-related complications. |
| Publish Date |
2019-10-28 11:23 |
| Citation |
Colussi G, Donnini D, Brizzi RF, Maier S, Velenti L, Catena C, Cavarape A, Sechi LA, Soardo G. Sustained virologic response to direct-acting antiviral agents predicts better outcomes in hepatitis C virus-infected patients: A retrospective study. World J Gastroenterol 2019; 25(40): 6094-6106 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i40/6094.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i40.6094 |
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