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Articles Published Processes
9/12/2019 8:50:34 AM | Browse: 745 | Download: 1066
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Received |
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2019-06-26 00:18 |
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Peer-Review Started |
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2019-06-26 08:09 |
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To Make the First Decision |
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2019-07-22 02:12 |
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Return for Revision |
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2019-07-22 07:48 |
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Revised |
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2019-07-25 13:48 |
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Second Decision |
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2019-08-02 10:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-08-07 09:27 |
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Articles in Press |
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2019-08-07 09:27 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-11 08:32 |
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Publish the Manuscript Online |
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2019-09-12 08:50 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Hepatic senescence, the good and the bad
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Nazmul Huda, Gang Liu, Honghai Hong, Shengmin Yan, Bilon Khambu and Xiao‐Ming Yin |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xiao‐Ming Yin, FAASLD, MD, PhD, Full Professor, Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, 975 W Walnut St, Indianapolis, IN 46202, United States. xmyin@iupui.edu |
| Key Words |
Senescence; Senescence associated secretory phenotype; Hepatocyte; Cholangiocyte; Hepatic stellate cell; Cell cycle arrest |
| Core Tip |
The liver is a vital organ for metabolic regulation and plays a major role in the nutrient utilization of the whole body. Although scientists have paid much attention to hepatic senescence, the precise mechanisms in, and the contribution of cellular senescence to liver diseases have yet to be clearly defined. In this review, we have summarized the mechanism of senescence in general and in the liver. We have also discussed whether hepatocellular senescence is beneficial or harmful to the liver in the light of published findings. |
| Publish Date |
2019-09-12 08:50 |
| Citation |
Huda N, Liu G, Hong H, Yan S, Khambu B, Yin X-M. Hepatic senescence, the good and the bad. World J Gastroenterol 2019; 25(34): 5069-5081 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i34/5069.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i34.5069 |
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