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Articles Published Processes
9/3/2014 2:27:00 PM | Browse: 1380 | Download: 1797
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Received |
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2013-08-08 08:57 |
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Peer-Review Started |
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2013-08-08 11:58 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2013-09-10 11:32 |
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Revised |
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2013-09-10 16:57 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2013-11-04 18:12 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2013-11-05 11:08 |
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Articles in Press |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-01-22 09:43 |
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Publish the Manuscript Online |
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2014-02-20 19:40 |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Autobiography |
| Article Title |
Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Chunqiu Chen, Jakub Fichna, Moshe Laudon and Martin Storr |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| University of Calgary Research Grant Committee |
to Storr M |
| Deutsche Forschungsgemeinschaft |
STO 645/6-1 |
| Deutsche Forschungsgemeinschaft |
645/9-1 (to Storr M) |
| Iuventus Plus program of the Polish Ministry of Science and Higher Education |
0119/IP1/2011/71 |
| Iuventus Plus program of the Polish Ministry of Science and Higher Education |
0107/IP1/2013/72 (to Fichna J) |
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| Corresponding Author |
Martin Storr, MD, PhD, Professor, Division of Gastroenterology, Department of Medicine, Ludwig Maximilians University of Munich, Marchioninistrasse 15, 81377 Munich, Germany. martin.storr@med.uni-muenchen.de |
| Key Words |
Gastrointestinal tract; Melatonin; Neu-P11; Neu-P12; Opioid; Visceral pain |
| Core Tip |
In search for new efficient therapies for the treatment of pain in the irritable bowel syndrome, the antinociceptive activity of two novel melatonin receptor agonists, Neu-P11 and Neu-P12, was characterized in a well-established mouse model of visceral pain. Neu-P12 produced a potent and long-lasting antinociceptive effect after intraperitoneal and oral administration. Further development of this novel compound for future treatment of abdominal pain seems promising. |
| Publish Date |
2014-02-20 19:40 |
| Citation |
Chen C, Fichna J, Laudon M, Storr M. Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain. World J Gastroenterol 2014; 20(5): 1298-1304
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| URL |
http://www.wjgnet.com/1007-9327/full/v20/i5/1298.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i5.1298 |
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