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9/3/2014 2:27:00 PM | Browse: 1026 | Download: 1169
Publication Name World Journal of Gastroenterology
Manuscript ID 4995
Country/Territory Germany
Received
2013-08-08 08:57
Peer-Review Started
2013-08-08 11:58
To Make the First Decision
2013-09-09 16:50
Return for Revision
2013-09-10 11:32
Revised
2013-09-10 16:57
Second Decision
2013-11-04 18:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-11-05 11:08
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-01-22 09:43
Publish the Manuscript Online
2014-02-20 19:40
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Autobiography
Article Title Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain
Manuscript Source Invited Manuscript
All Author List Chunqiu Chen, Jakub Fichna, Moshe Laudon and Martin Storr
Funding Agency and Grant Number
Funding Agency Grant Number
University of Calgary Research Grant Committee to Storr M
Deutsche Forschungsgemeinschaft STO 645/6-1
Deutsche Forschungsgemeinschaft 645/9-1 (to Storr M)
Iuventus Plus program of the Polish Ministry of Science and Higher Education 0119/IP1/2011/71
Iuventus Plus program of the Polish Ministry of Science and Higher Education 0107/IP1/2013/72 (to Fichna J)
Corresponding Author Martin Storr, MD, PhD, Professor, Division of Gastroenterology, Department of Medicine, Ludwig Maximilians University of Munich, Marchioninistrasse 15, 81377 Munich, Germany. martin.storr@med.uni-muenchen.de
Key Words Gastrointestinal tract; Melatonin; Neu-P11; Neu-P12; Opioid; Visceral pain
Core Tip In search for new efficient therapies for the treatment of pain in the irritable bowel syndrome, the antinociceptive activity of two novel melatonin receptor agonists, Neu-P11 and Neu-P12, was characterized in a well-established mouse model of visceral pain. Neu-P12 produced a potent and long-lasting antinociceptive effect after intraperitoneal and oral administration. Further development of this novel compound for future treatment of abdominal pain seems promising.
Publish Date 2014-02-20 19:40
Citation Chen C, Fichna J, Laudon M, Storr M. Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain. World J Gastroenterol 2014; 20(5): 1298-1304
URL http://www.wjgnet.com/1007-9327/full/v20/i5/1298.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i5.1298
Full Article (PDF) WJG-20-1298.pdf
Full Article (Word) WJG-20-1298.doc
Manuscript File 4995-Review.doc
Answering Reviewers 4995-Answering reviewers.pdf
Copyright License Agreement 4995-Copyright assignment.pdf
Peer-review Report 4995-Peer reviews.pdf
Scientific Editor Work List 4995-Scientific editor work list.doc