Publication Name	World Journal of Clinical Oncology
Manuscript ID	50169
Country	Spain

Received	2019-07-05 00:43
Peer-Review Started	2019-07-17 08:51
To Make the First Decision	2019-10-15 00:20
Return for Revision	2019-10-15 00:50
Revised	2019-11-13 09:10
Second Decision	2019-11-15 08:08
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2019-11-19 04:19
Articles in Press	2019-11-19 04:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-12-18 07:19
Publish the Manuscript Online	2019-12-26 00:19

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Editorial
Article Title	Are all prostate cancer patients "fit" for salvage radiotherapy?
Manuscript Source	Invited Manuscript
All Author List	Carmen González-San Segundo, Alfonso Gómez-Iturriaga and Felipe Couñago
ORCID	Author(s) ORCID Number Carmen González-San Segundo http://orcid.org/0000-0002-5489-5327 Alfonso Gómez-Iturriaga http://orcid.org/0000-0002-1094-5839 Felipe Couñago http://orcid.org/0000-0001-7233-0234
Funding Agency and Grant Number
Corresponding Author	Carmen González-San Segundo, MD, PhD, Professor, Research Scientist, Staff Physician, Department of Radiation Oncology, HGU Gregorio Marañon, Complutense University, C/Doctor Esquerdo 46, Madrid 28007, Spain. cglezss@gmail.com
Key Words	Prostate cancer; Salvage radiotherapy; Comorbidity; Fit; Androgen deprivation therapy;
Core Tip	Salvage radiotherapy (SRT) is an effective treatment for biochemically-recurrent prostate cancer after prostatectomy. Proper patient selection is crucial. While tumour-related factors are important, the indication for SRT should also be based on clinical factors and dosimetric variables. Patients with non-aggressive tumours who have a life expectancy of less than 10 years are unlikely to benefit from radiotherapy and should thus be considered "unfit" for SRT. The development of advanced imaging techniques such Ga-PSMA positron emission tomography/computed tomography, which are capable of localizing the recurrent lesion when prostate-specific antigen ≤ 0.5 ng/mL, has forced clinicians to reconsider whether patients should undergo radiotherapy without locate first the recurrence.
Publish Date	2019-12-26 00:19
Citation	González-San Segundo C, Gómez-Iturriaga A, Couñago F. Are all prostate cancer patients "fit" for salvage radiotherapy? World J Clin Oncol 2020; 11(1): 1-10
URL	https://www.wjgnet.com/2218-4333/full/v11/i1/1.htm
DOI	https://dx.doi.org/10.5306/wjco.v11.i1.1

Full Article (PDF)	WJCO-11-1.pdf
Full Article (Word)	WJCO-11-1.docx
Manuscript File	50169-Review.doc
Answering Reviewers	50169-Answering reviewers.pdf
Audio Core Tip	50169-Audio core tip.wav
Conflict-of-Interest Disclosure Form	50169-Conflict-of-interest statement.pdf
Copyright License Agreement	50169-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	50169-Language certificate.pdf
Peer-review Report	50169-Peer-review(s).pdf
Scientific Misconduct Check	50169-Scientific misconduct check.pdf
Scientific Editor Work List	50169-Scientific editor work list.pdf
CrossCheck Report	50169-CrossCheck Report.pdf