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Articles Published Processes
11/14/2019 9:43:48 AM | Browse: 782 | Download: 1191
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Received |
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2019-07-21 06:58 |
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Peer-Review Started |
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2019-07-22 08:53 |
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To Make the First Decision |
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2019-08-28 01:50 |
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Return for Revision |
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2019-09-04 09:12 |
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Revised |
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2019-09-27 07:25 |
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Second Decision |
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2019-10-28 10:35 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-11-01 01:46 |
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Articles in Press |
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2019-11-01 01:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-11-07 13:27 |
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Typeset the Manuscript |
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2019-11-14 00:44 |
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Publish the Manuscript Online |
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2019-11-14 09:43 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Knockdown of lncRNAXLOC_001659 inhibited proliferation and invasion of esophageal squamous cell carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Feng-Zhi Li and Wen-Qiao Zang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Excellent Youth Development Fund |
1621328001 |
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| Corresponding Author |
Wen-Qiao Zang, PhD, Assistant Professor, College of Basic Medical Sciences, Zhengzhou University, No.100 Kexue Road, Zhengzhou 450000, Henan Province, China. zangwenqiao@zzu.edu.cn |
| Key Words |
Esophageal squamous cell carcinoma; LncRNAXLOC_001659; MiR-490-5p; PIK3CA; Proliferation; Invasion |
| Core Tip |
Studies have shown that long non-coding RNAs (lncRNAs) play a key role in almost all key physiological and pathological processes, including different types of malignant tumors. Our previous lncRNA microarray results have shown that lncRNA XLOC_001659 is upregulated in esophageal squamous cell carcinoma (ESCC) tissues, with the fold-change value of 20.9 relative to normal esophageal tissues. But its effect and the molecular biological mechanisms on proliferation and invasion of ESCC cells remain unclear. Our results showed that knockdown of lncRNA XLOC_001659 inhibited proliferation and invasion of esophageal squamous cell carcinoma via regulation of miR-490-5p/PIK3CA, suggesting that it may play a role in ESCC tumorigenesis and progression. |
| Publish Date |
2019-11-14 09:43 |
| Citation |
Li FZ, Zang WQ. Knockdown of lncRNAXLOC_001659 inhibited proliferation and invasion of esophageal squamous cell carcinoma. World J Gastroenterol 2019; 25(42): 6299-6310 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i42/6299.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i42.6299 |
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