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Articles Published Processes
10/21/2019 9:37:00 AM | Browse: 1230 | Download: 2597
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Received |
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2019-08-01 13:12 |
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Peer-Review Started |
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2019-08-01 13:12 |
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First Decision by Editorial Office Director |
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2019-08-27 22:18 |
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Return for Revision |
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2019-09-04 08:40 |
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Revised |
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2019-09-06 17:15 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2019-09-20 09:11 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2019-09-28 04:43 |
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Articles in Press |
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2019-09-28 04:43 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-10-18 05:03 |
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Publish the Manuscript Online |
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2019-10-21 09:37 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Role of tristetraprolin phosphorylation in paediatric patients with inflammatory bowel disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Alessia Di Silvestre, Marianna Lucafò, Letizia Pugnetti, Matteo Bramuzzo, Gabriele Stocco, Egidio Barbi and Giuliana Decorti |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Italian Ministry of Health projects |
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| Ricerca Corrente 1/17 and 21/17 of the Institute for Maternal and Child Health IRCCS Burlo Garofolo |
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| Corresponding Author |
Giuliana Decorti, MD, Full Professor, Department of Medical, Surgical and Health Sciences, University of Trieste, Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, Via A. Fleming 22, Trieste, I-34127, Trieste 34127, Italy. decorti@units.it |
| Key Words |
Inflammatory bowel disease; Tristetraprolin; 14-3-3 protein; Phosphorylation; Cytokine; Inflammation |
| Core Tip |
We report a preliminary study describing the role of tristetraprolin (TTP)/14-3-3 complex in a small cohort of paediatric patients affected by inflammatory bowel disease (IBD). The experiments were conducted on IBD inflamed and non-inflamed colonic tissues and IBD-derived macrophages respect to heathy donors’. This study demonstrates for the first time the relation between the phosphorylation of TTP and paediatric IBD patients. Indeed, a higher expression of TTP/14-3-3 complex was recorder both in inflamed colon specimens compared to non-inflamed and in IBD-derived macrophages respect to healthy donors. |
| Publish Date |
2019-10-21 09:37 |
| Citation |
Di Silvestre A, Lucafò M, Pugnetti L, Bramuzzo M, Stocco G, Barbi E, Decorti G. Role of tristetraprolin phosphorylation in paediatric patients with inflammatory bowel disease. World J Gastroenterol 2019; 25(39): 5918-5925 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i39/5918.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i39.5918 |
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