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10/24/2019 1:56:03 AM | Browse: 677 | Download: 975
Publication Name World Journal of Hepatology
Manuscript ID 50453
Country Singapore
Received
2019-07-21 06:12
Peer-Review Started
2019-07-24 10:33
To Make the First Decision
2019-08-14 06:52
Return for Revision
2019-08-14 07:09
Revised
2019-08-20 05:51
Second Decision
2019-09-29 05:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-10-02 17:57
Articles in Press
2019-10-02 17:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-10-22 08:22
Publish the Manuscript Online
2019-10-24 01:56
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019 Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Case Report
Article Title Escitalopram-induced liver injury: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Qin Xiang Ng, Christl Suet Kwan Yong, Wayren Loke, Wee Song Yeo and Alex Yu Sen Soh
ORCID
Author(s) ORCID Number
Qin Xiang Ng http://orcid.org/0000-0001-8561-2513
Christl Suet Kwan Yong http://orcid.org/0000-0003-3437-9891
Wayren Loke http://orcid.org/0000-0003-4498-9773
Wee Song Yeo http://orcid.org/0000-0002-2201-2673
Alex Yu Sen Soh http://orcid.org/0000-0002-1981-1941
Funding Agency and Grant Number
Corresponding Author Qin Xiang Ng, MBBS, Institute of Mental Health, Buangkok Green Medical Park, 10 Buangkok View, Singapore 329506, Singapore. ng.qin.xiang@u.nus.edu
Key Words Depression; Antidepressant; Escitalopram; Liver injury; Drug-induced; Drug-induced liver injury
Core Tip We herein report a probable case of escitalopram-induced liver injury. A 56-year-old Chinese lady presented with fever and cholestatic liver injury two weeks after initiation of escitalopram for the treatment of psychotic depression. Physical examination and investigations for stones, viral hepatitis and autoimmune liver disease were unyielding. Upon stopping escitalopram, repeat liver function tests showed downtrending liver enzymes with eventual normalization of serum aminotransferase levels. Clinicians should be aware of the possibility of drug-induced liver injury associated with escitalopram use, when initiating depressed patients on antidepressant treatment. This requires extra vigilance as most patients may remain asymptomatic.
Publish Date 2019-10-24 01:56
Citation Ng QX, Yong CSK, Loke W, Yeo WS, Soh AYS. Escitalopram-induced liver injury: A case report and review of literature. World J Hepatol 2019; 11(10): 719-724
URL https://www.wjgnet.com/1948-5182/full/v11/i10/719.htm
DOI https://dx.doi.org/10.4254/wjh.v11.i10.719
Full Article (PDF) WJH-11-719.pdf
Full Article (Word) WJH-11-719.docx
Manuscript File 50453-Review.docx
Answering Reviewers 50453-Answering reviewers.pdf
Audio Core Tip 50453-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 50453-Conflict-of-interest statement.pdf
Copyright License Agreement 50453-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 50453-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 50453-Language certificate.pdf
Peer-review Report 50453-Peer-review(s).pdf
Scientific Misconduct Check 50453-Scientific misconduct check.pdf
Scientific Editor Work List 50453-Scientific editor work list.pdf