Publication Name	World Journal of Meta-Analysis
Manuscript ID	50600
Country	Nigeria

Received	2019-07-29 17:02
Peer-Review Started	2019-07-29 17:04
To Make the First Decision	2019-08-22 00:11
Return for Revision	2019-08-22 02:47
Revised	2019-10-20 08:32
Second Decision	2019-10-29 10:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2019-10-29 17:50
Articles in Press	2019-10-29 17:50
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-11-04 20:15
Typeset the Manuscript	2019-11-14 07:47
Publish the Manuscript Online	2019-12-02 06:57

ISSN	2308-3840 (online)
Open Access
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Biochemistry & Molecular Biology
Manuscript Type	Minireviews
Article Title	Mechanism of action of aqueous extract of hunteria umbellata seed and metformin in diabetes
Manuscript Source	Unsolicited Manuscript
All Author List	Oluwamodupe Cecilia Ejelonu
ORCID	Author(s) ORCID Number Oluwamodupe Cecilia Ejelonu http://orcid.org/0000-00017881-8134
Funding Agency and Grant Number
Corresponding Author	Oluwamodupe Cecilia Ejelonu, PhD, Lecturer, Department of Chemical Sciences, Biochemistry Programme, Ondo State University of Science and Technology, Okitipupa, Ondo State, Okitipupa 23111, Ondo State, Nigeria. oc.ejelonu@osustech.edu.ng
Key Words	Insulin; Diabetes; Hunteria umbellate; Metformin; Metabolic syndrome; -
Core Tip	Herbs have been used for medicinal purposes since time immemorial, though concerns exist about quality, safety, dosage and mechanism of action of herbal medicinal products. This mini review reveals some insight about Hunteria umbellata seed, similar to metformin Insulin secretagogue with less side effect in diabetic subject. Based on its beneficial roles that have been documented, none of the studies have evaluated mechanisms involved. Therefore, researchers in this field who are passionate in drug design need to consider the below pathways for Hunteria umbellata seed; which may serve as new therapeutic strategy for type-2 diabetes in place of metformin.
Publish Date	2019-12-02 06:57
Citation	Ejelonu OC. Mechanism of action of aqueous extract of hunteria umbellata seed and metformin in diabetes. World J Meta-Anal 2019; 7(9): 418-422
URL	https://www.wjgnet.com/2308-3840/full/v7/i9/418.htm
DOI	https://dx.doi.org/10.13105/wjma.v7.i9.418

Full Article (PDF)	WJMA-7-418.pdf
Full Article (Word)	WJMA-7-418.docx
Manuscript File	FP7068_ce25_CE1MS-edit2 OC Ejelonu.docx
Answering Reviewers	50600-Answering reviewers.pdf
Audio Core Tip	50600-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	50600-Conflict-of-interest statement.pdf
Copyright License Agreement	50600-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	50600-Language certificate.pdf
Peer-review Report	50600-Peer-review(s).pdf
Scientific Misconduct Check	50600-Scientific misconduct check.pdf
Scientific Editor Work List	50600-Scientific editor work list.pdf
CrossCheck Report	50600-CrossCheck report.pdf