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Articles Published Processes
11/7/2019 1:35:59 AM | Browse: 709 | Download: 1342
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Received |
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2019-08-12 15:47 |
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Peer-Review Started |
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2019-08-12 15:48 |
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To Make the First Decision |
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2019-08-28 01:51 |
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Return for Revision |
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2019-09-04 03:13 |
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Revised |
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2019-09-26 15:07 |
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Second Decision |
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2019-10-16 12:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-10-17 06:15 |
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Articles in Press |
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2019-10-17 06:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-10-25 02:52 |
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Typeset the Manuscript |
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2019-11-05 02:21 |
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Publish the Manuscript Online |
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2019-11-07 01:35 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Basic Study |
| Article Title |
Therapeutic potential of menstrual blood stem cells treating acute liver failure
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Pan-Pan Cen, Lin-Xiao Fan, Jie Wang, Jia-Jia Chen and Lan-Juan Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the State Key Laboratory for Diagnosis and Treatment of Infectious Disease |
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| Corresponding Author |
Lan-Juan Li, MD, PhD, Academic Research, Doctor, Doctor, Professor, Senior Researcher, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases; National Clinical Research Center for Infectious Diseases;, First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road 48, Shangcheng District, Hangzhou 310006, Zhejiang Province, China. ljli@zju.edu.cn |
| Key Words |
Menstrual blood stem cell; Acute liver failure; Cell transplantation; Homing; Labelling; |
| Core Tip |
In this study, we explored for the first time the therapeutic potential of intraportally transplanted menstrual blood stem cells (MenSCs) in treating pigs with acute liver failure, and showed that MenSC treatment improved liver function and coagulation, alleviated the progression of liver injury, and prolonged the survival time of pigs. Additionally, ex vivo imaging results also demonstrated the ability of MenSCs homing to pathological hepatic environments post transplantation. MenSC transplantation has the potential to be used as an available source for treating acute liver failure in future clinical therapy. |
| Publish Date |
2019-11-07 01:35 |
| Citation |
Cen PP, Fan LX, Wang J, Chen JJ, Li LJ. Therapeutic potential of menstrual blood stem cells treating acute liver failure. World J Gastroenterol 2019; 25(41): 6190-6204 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i41/6190.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i41.6190 |
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