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Articles Published Processes
2/6/2020 2:37:44 AM | Browse: 709 | Download: 1060
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Received |
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2019-09-03 09:01 |
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Peer-Review Started |
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2019-09-03 09:02 |
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To Make the First Decision |
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2019-10-18 01:47 |
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Return for Revision |
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2019-10-18 08:57 |
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Revised |
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2019-12-14 15:58 |
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Second Decision |
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2019-12-19 02:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-12-22 14:27 |
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Articles in Press |
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2019-12-22 14:27 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-12-30 13:46 |
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Publish the Manuscript Online |
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2020-02-06 02:37 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Engineering, Biomedical |
Manuscript Type |
Clinical and Translational Research |
Article Title |
Novel zinc alloys for biodegradable surgical staples
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Hizuru Amano, Koichi Miyake, Akinari Hinoki, Kazuki Yokota, Fumie Kinoshita, Atsuko Nakazawa, Yujiro Tanaka, Yasuhiro Seto and Hiroo Uchida |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Hiroo Uchida, MD, PhD, Doctor, Doctor, Professor, Department of Pediatric Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Syowa-ku, Nagoya 4668550, Aichi, Japan. hiro2013@med.nagoya-u.ac.jp |
Key Words |
Zinc alloy; Surgical staple; Gastric resection; Biodegradability; Biocompatibility; Mechanical strength |
Core Tip |
Biodegradable Zn alloy can be prepared with adequate strength, ductility, biodegradability, and biocompatibility for use as surgical staples by alloying with ≤1 wt.% Mn or Cu and 0.1 wt.% Ti. Immersion tests reveal no gas evolution or staple fracture. In vivo, none of the Zn alloy staples cause technical failure, and all rabbits survive without complications. The degradation times are sufficient for wound healing. The degradation rate is increased under low pH conditions, suggesting staples used for resection or anastomosis of gastrointestinal tracts would degrade faster, as they are exposed to acidic digestive fluids. |
Publish Date |
2020-02-06 02:37 |
Citation |
Amano H, Miyake K, Hinoki A, Yokota K, Kinoshita F, Nakazawa A, Tanaka Y, Seto Y, Uchida H. Novel zinc alloys for biodegradable surgical staples. World J Clin Cases 2020; 8(3): 504-516 |
URL |
https://www.wjgnet.com/2307-8960/full/v8/i3/504.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v8.i3.504 |
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