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Articles Published Processes
2/14/2020 11:49:18 AM | Browse: 1005 | Download: 1767
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Received |
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2019-08-13 09:14 |
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Peer-Review Started |
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2019-08-13 09:14 |
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To Make the First Decision |
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2019-10-14 08:55 |
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Return for Revision |
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2019-10-17 02:43 |
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Revised |
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2019-12-25 01:31 |
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Second Decision |
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2020-01-08 09:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-01-11 14:20 |
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Articles in Press |
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2020-01-11 14:20 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-01-16 21:24 |
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Typeset the Manuscript |
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2020-02-10 09:44 |
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Publish the Manuscript Online |
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2020-02-14 11:49 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Basic Study |
Article Title |
Characterizing the composition of intestinal microflora by 16S rRNA gene sequencing
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Wen-Jia Wang, You-Lian Zhou, Jie He, Zhi-Qiang Feng, Long Zhang, Xiao-Bo Lai, Jun-Xiao Zhou and Hong Wang |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Guangdong Provincial Department of Science and Technology |
2014A020212568 |
National Key Clinical Specialized Special Funds Programs of China |
2013544 |
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Corresponding Author |
Hong Wang, MD, PhD, Chief Physician, Department of Gastroenterology,Guangzhou Digestive Disease Center, Guangzhou First People’s Hospital, South China University of Technology, No. 1 Panfu road, Yuexiu district, Guangzhou 510030, Guangdong Province, China. wong.hong@163.com |
Key Words |
16S rDNA; Intestinal microflora; Advanced colorectal adenoma; Colorectal cancer; Biomarkers; |
Core Tip |
Colorectal adenoma (CRA), as the most important pre-cancerous lesion of colorectal cancer, has a close relationship with the intestinal microflora. But the mechanism is not clear. Early detection of CRA can effectively reduce the morbidity and mortality of colorectal cancer. This paper analyzes the composition and diversity of intestinal microflora in patients with CRA through 16s rDNA gene sequencing. It was proved that the diversity of intestinal microflora in patients with CRA decreased, and the increase in the number of Halomonadaceae and Shewanella algae may be biomarkers of CRA, which provides a basis for future research. |
Publish Date |
2020-02-14 11:49 |
Citation |
Wang WJ, Zhou YL, He J, Feng ZQ, Zhang L, Lai XB, Zhou JX, Wang H. Characterizing the composition of intestinal microflora by 16S rRNA gene sequencing. World J Gastroenterol 2020; 26(6): 614-626 |
URL |
https://www.wjgnet.com/1007-9327/full/v26/i6/614.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v26.i6.614 |
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