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2/24/2020 2:37:58 AM | Browse: 854 | Download: 1243
Publication Name World Journal of Clinical Oncology
Manuscript ID 51075
Country/Territory Portugal
Received
2019-08-24 23:55
Peer-Review Started
2019-08-24 23:56
To Make the First Decision
Return for Revision
2019-11-20 23:29
Revised
2019-12-13 22:28
Second Decision
2019-12-18 09:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-12-20 05:33
Articles in Press
2019-12-20 05:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-12-30 04:32
Publish the Manuscript Online
2020-02-24 02:37
ISSN 2218-4333 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Review
Article Title Can epigenetic and inflammatory biomarkers identify clinically aggressive prostate cancer?
Manuscript Source Unsolicited Manuscript
All Author List Pedro Bargão Santos, Hitendra Patel, Rui Henrique and Ana Félix
ORCID
Author(s) ORCID Number
Pedro Bargão Santos http://orcid.org/0000-0002-4750-4754
Hitendra Patel http://orcid.org/0000-0001-8746-2600
Rui Henrique http://orcid.org/0000-0003-3171-4666
Ana Félix http://orcid.org/0000-0002-2653-2262
Funding Agency and Grant Number
Corresponding Author Pedro Bargão Santos, MD, Medical Assistant, Senior Researcher, Surgeon, Surgical Oncologist, Department of Urology, Prof. Doutor Fernando Fonseca Hospital, IC 19, Lisbon 1150-155, Lisboa, Portugal. pbargao@gmail.com
Key Words Prostate cancer; Epigenetics; DNA methylation; Histone modifications; MicroRNAs; Inflammation
Core Tip Epigenetic modifications are a common feature of prostate cancer (PCa) and play an important role in prostate carcinogenesis as well as in disease progression. Two important recent discoveries were the presence of resident microbial species in the urinary tract and their role in the initiation of chronic inflammation, proliferative inflammatory atrophy and development of PCa. Facts that may explain the higher prevalence of PCa in western countries include elevated inflammation due to metabolic syndrome and associated comorbidities. It is essential to completely characterize the link between these facts to allow the development of strategies for PCa prevention.
Publish Date 2020-02-24 02:37
Citation Santos PB, Patel H, Henrique R, Félix A. Can epigenetic and inflammatory biomarkers identify clinically aggressive prostate cancer? World J Clin Oncol 2020; 11(2): 43-52
URL https://www.wjgnet.com/2218-4333/full/v11/i2/43.htm
DOI https://dx.doi.org/10.5306/wjco.v11.i2.43
Full Article (PDF) WJCO-11-43.pdf
Full Article (Word) WJCO-11-43.docx
Manuscript File 51075-Review.docx
Answering Reviewers 51075-Answering reviewers.pdf
Audio Core Tip 51075-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 51075-Conflict-of-interest statement.pdf
Copyright License Agreement 51075-Copyright license agreement.docx
Non-Native Speakers of English Editing Certificate 51075-Language certificate.pdf
Peer-review Report 51075-Peer-review(s).pdf
Scientific Misconduct Check 51075-Scientific misconduct check.pdf
Scientific Editor Work List 51075-Scientific editor work list.pdf