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Articles Published Processes
2/24/2020 2:37:58 AM | Browse: 1025 | Download: 1627
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Received |
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2019-08-24 23:55 |
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Peer-Review Started |
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2019-08-24 23:56 |
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To Make the First Decision |
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Return for Revision |
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2019-11-20 23:29 |
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Revised |
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2019-12-13 22:28 |
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Second Decision |
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2019-12-18 09:02 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-12-20 05:33 |
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Articles in Press |
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2019-12-20 05:33 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-12-30 04:32 |
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Publish the Manuscript Online |
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2020-02-24 02:37 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Review |
| Article Title |
Can epigenetic and inflammatory biomarkers identify clinically aggressive prostate cancer?
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Pedro Bargão Santos, Hitendra Patel, Rui Henrique and Ana Félix |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Pedro Bargão Santos, MD, Medical Assistant, Senior Researcher, Surgeon, Surgical Oncologist, Department of Urology, Prof. Doutor Fernando Fonseca Hospital, IC 19, Lisbon 1150-155, Lisboa, Portugal. pbargao@gmail.com |
| Key Words |
Prostate cancer; Epigenetics; DNA methylation; Histone modifications; MicroRNAs; Inflammation |
| Core Tip |
Epigenetic modifications are a common feature of prostate cancer (PCa) and play an important role in prostate carcinogenesis as well as in disease progression. Two important recent discoveries were the presence of resident microbial species in the urinary tract and their role in the initiation of chronic inflammation, proliferative inflammatory atrophy and development of PCa. Facts that may explain the higher prevalence of PCa in western countries include elevated inflammation due to metabolic syndrome and associated comorbidities. It is essential to completely characterize the link between these facts to allow the development of strategies for PCa prevention. |
| Publish Date |
2020-02-24 02:37 |
| Citation |
Santos PB, Patel H, Henrique R, Félix A. Can epigenetic and inflammatory biomarkers identify clinically aggressive prostate cancer? World J Clin Oncol 2020; 11(2): 43-52 |
| URL |
https://www.wjgnet.com/2218-4333/full/v11/i2/43.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v11.i2.43 |
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