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Articles Published Processes
11/7/2019 1:35:59 AM | Browse: 808 | Download: 1772
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Received |
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2019-08-27 09:45 |
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Peer-Review Started |
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2019-08-27 09:47 |
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To Make the First Decision |
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2019-09-19 06:33 |
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Return for Revision |
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2019-09-20 03:31 |
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Revised |
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2019-10-11 15:19 |
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Second Decision |
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2019-10-16 12:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-10-21 18:12 |
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Articles in Press |
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2019-10-21 18:12 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-10-31 01:15 |
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Typeset the Manuscript |
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2019-11-05 00:01 |
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Publish the Manuscript Online |
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2019-11-07 01:35 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Basic Study |
| Article Title |
MiR-32-5p aggravates intestinal epithelial cell injury of pediatric enteritis induced by Helicobacter pylori
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jing Feng, Jian Guo, Jun-Ping Wang and Bao-Feng Chai |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bao-Feng Chai, MD, PhD, Professor, Department of Gastroenterology, Shanxi Provincial People's Hospital, The Affiliated People's Hospital of Shanxi Medical University, NO. 29, Shuangtasi Street, Taiyuan 030012, Shanxi Province, China. 13644359409@163.com |
| Key Words |
MiR-32-5p; SMAD family member 6; Transforming growth factor-β-activated kinase 1; Apoptosis; Enteritis; Helicobacter pylori |
| Core Tip |
Our study demonstrated the harmful role of aberrant miR-35-5p in H. pylori-infected intestinal epithelial cells. Further investigation showed SMAD6 was the downstream of miR-32-5p and exerted the opposite role in this process. What’s more, miR-32-5p/SMAD6 contributed to TGF-β1-TAK1-p38 cascade in intestinal epithelial cells under H. pylori infection. These findings revealed a novel insight into the pathogenesis of pediatric enteritis caused by H. pylori. |
| Publish Date |
2019-11-07 01:35 |
| Citation |
Feng J, Guo J, Wang JP, Chai BF. miR-32-5p aggravates intestinal epithelial cell injury of pediatric enteritis induced by Helicobacter pylori. World J Gastroenterol 2019; 25(41): 6222-6237 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i41/6222.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i41.6222 |
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