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Articles Published Processes
4/28/2020 11:19:00 AM | Browse: 871 | Download: 1350
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Received |
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2019-09-17 08:14 |
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Peer-Review Started |
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2019-09-17 08:14 |
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To Make the First Decision |
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2019-11-15 01:00 |
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Return for Revision |
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2019-11-19 09:08 |
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Revised |
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2020-01-14 18:11 |
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Second Decision |
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2020-02-27 08:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-02-28 06:46 |
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Articles in Press |
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2020-02-28 06:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-03-06 01:01 |
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Typeset the Manuscript |
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2020-03-23 01:25 |
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Publish the Manuscript Online |
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2020-04-28 11:19 |
ISSN |
2308-3840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Biochemistry & Molecular Biology |
Manuscript Type |
Review |
Article Title |
Hypoxia and oxidative stress: The role of the anaerobic gut, the hepatic arterial buffer response and other defence mechanisms of the liver
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Samapriya Pasan Hewawasam |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Samapriya Pasan Hewawasam, MBBS, MD, Freelancing Philosopher, Senior Lecturer, Department of Physiology, Faculty of Medicine, University of Ruhuna, Karapitiya, Galle 80000, Sri Lanka. spasanhewawasam@yahoo.com |
Key Words |
Anaerobic gut lumen; Oxidative stress; Liver defences against oxidative stress; Hepatic arterial buffer response; Hypoxia; Liver function |
Core Tip |
This review presents a prototypic view of the role of hypoxia as a regulator and a defence mechanism against oxidative stress in the gastrointestinal tract, including in the liver. The functional significance of having an anaerobic gut lumen for the preservation of energy sources is described in the article. Further, the significance of the hepatic arterial buffer response in the maintenance of the hypoxic microenvironment of hepatocytes to regulate the oxidative stress generated by the enormous catalytic potential of the liver and other hypoxia-mediated defences against this oxidative stress are described here. |
Publish Date |
2020-04-28 11:19 |
Citation |
Hewawasam SP. Hypoxia and oxidative stress: The role of the anaerobic gut, the hepatic arterial buffer response and other defence mechanisms of the liver. World J Meta-Anal 2020; 8(2): 78-88 |
URL |
https://www.wjgnet.com/2308-3840/full/v8/i2/78.htm |
DOI |
https://dx.doi.org/10.13105/wjma.v8.i2.78 |
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