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4/28/2020 11:19:00 AM | Browse: 198 | Download: 162
Publication Name World Journal of Meta-Analysis
Manuscript ID 51457
Country/Territory Sri Lanka
2019-09-17 08:14
Peer-Review Started
2019-09-17 08:14
To Make the First Decision
2019-11-15 01:00
Return for Revision
2019-11-19 09:08
2020-01-14 18:11
Second Decision
2020-02-27 08:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-02-28 06:46
Articles in Press
2020-02-28 06:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-03-06 01:01
Typeset the Manuscript
2020-03-23 01:25
Publish the Manuscript Online
2020-04-28 11:19
ISSN 2308-3840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemistry and Molecular Biology
Manuscript Type Review
Article Title Hypoxia and oxidative stress: The role of the anaerobic gut, the hepatic arterial buffer response and other defence mechanisms of the liver
Manuscript Source Unsolicited Manuscript
All Author List Samapriya Pasan Hewawasam
Author(s) ORCID Number
Samapriya Pasan Hewawasam http://orcid.org/0000-0002-9894-4661
Funding Agency and Grant Number
Corresponding Author Samapriya Pasan Hewawasam, MBBS, MD, Freelancing Philosopher, Senior Lecturer, Department of Physiology, Faculty of Medicine, University of Ruhuna, Karapitiya, Galle 80000, Sri Lanka. spasanhewawasam@yahoo.com
Key Words Anaerobic gut lumen; Oxidative stress; Liver defences against oxidative stress; Hepatic arterial buffer response; Hypoxia; Liver function
Core Tip This review presents a prototypic view of the role of hypoxia as a regulator and a defence mechanism against oxidative stress in the gastrointestinal tract, including in the liver. The functional significance of having an anaerobic gut lumen for the preservation of energy sources is described in the article. Further, the significance of the hepatic arterial buffer response in the maintenance of the hypoxic microenvironment of hepatocytes to regulate the oxidative stress generated by the enormous catalytic potential of the liver and other hypoxia-mediated defences against this oxidative stress are described here.
Publish Date 2020-04-28 11:19
Citation Hewawasam SP. Hypoxia and oxidative stress: The role of the anaerobic gut, the hepatic arterial buffer response and other defence mechanisms of the liver. World J Meta-Anal 2020; 8(2): 78-88
URL https://www.wjgnet.com/2308-3840/full/v8/i2/78.htm
DOI https://dx.doi.org/10.13105/wjma.v8.i2.78
Full Article (PDF) WJMA-8-78.pdf
Full Article (Word) WJMA-8-78.docx
Manuscript File 51457-Review-Webster J.docx
Answering Reviewers 51457-Answering reviewers.pdf
Audio Core Tip 51457-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 51457-Conflict-of-interest statement.pdf
Copyright License Agreement 51457-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 51457-Language certificate.pdf
Peer-review Report 51457-Peer-review(s).pdf
Scientific Misconduct Check 51457-Scientific misconduct check.pdf
Scientific Editor Work List 51457-Scientific editor work list.pdf