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Articles Published Processes
8/12/2020 9:10:19 AM | Browse: 781 | Download: 1574
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Received |
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2019-12-30 16:17 |
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Peer-Review Started |
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2019-12-30 16:18 |
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To Make the First Decision |
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Return for Revision |
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2020-02-20 06:08 |
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Revised |
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2020-05-29 10:44 |
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Second Decision |
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2020-06-12 08:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-06-14 19:18 |
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Articles in Press |
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2020-06-14 19:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-06-22 20:51 |
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Typeset the Manuscript |
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2020-07-30 09:47 |
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Publish the Manuscript Online |
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2020-08-12 09:10 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Comparison of hyperthermic intraperitoneal chemotherapy regimens for treatment of peritoneal-metastasized colorectal cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Julia Spiegelberg, Hannes Neeff, Philipp Holzner, Mira Runkel, Stefan Fichtner-Feigl and Torben Glatz |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Torben Glatz, MD, Adjunct Professor, Surgeon, Department of Surgery, Marien Hospital Herne, Ruhr-University Bochum, Hölkeskampring 40, Herne 44625, Germany. torben.glatz@uniklinik-freiburg.de |
| Key Words |
Colorectal cancer; Peritoneal carcinomatosis; Cytoreductive surgery; Hyperthermic intraperitoneal chemotherapy; Chemotherapy efficacy; Mitomycin |
| Core Tip |
We evaluated the therapeutic efficiency of cytoreductive surgery (CRS) in combination with two different hyperthermic intraperitoneal chemotherapy (HIPEC) regimens, comparing mitomycin C (MMC) HIPEC vs oxaliplatin HIPEC. We therefore retrospectively evaluated 102 patients undergoing CRS and HIPEC and statistically analysed demographics, perioperative complication and survival outcome. We found no difference in median overall survival between MMC and oxaliplatin HIPEC. Regarding postoperative complications, patients treated with oxaliplatin HIPEC suffered an increased complication rate. Regarding multivariate analysis of survival, primary distant metastasis and primary tumor resection seem to have a significant impact on survival and likewise peritoneal cancer index-scoring regarding peritoneal carcinomatosis. Further prospective studies comparing HIPEC regimens, would improve therapeutic decision-making. |
| Publish Date |
2020-08-12 09:10 |
| Citation |
Spiegelberg J, Neeff H, Holzner P, Runkel M, Fichtner-Feigl S, Glatz T. Comparison of hyperthermic intraperitoneal chemotherapy regimens for treatment of peritoneal-metastasized colorectal cancer. World J Gastrointest Oncol 2020; 12(8): 903-917 |
| URL |
https://www.wjgnet.com/1948-5204/full/v12/i8/903.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v12.i8.903 |
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