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Articles Published Processes
2/28/2020 3:42:19 AM | Browse: 793 | Download: 1395
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Received |
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2019-10-03 09:22 |
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Peer-Review Started |
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2019-10-03 09:22 |
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To Make the First Decision |
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Return for Revision |
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2019-11-10 05:28 |
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Revised |
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2019-12-20 12:44 |
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Second Decision |
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2020-02-11 11:21 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-02-11 19:34 |
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Articles in Press |
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2020-02-11 19:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-02-14 08:19 |
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Typeset the Manuscript |
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2020-02-26 08:13 |
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Publish the Manuscript Online |
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2020-02-28 03:42 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Promising key genes associated with tumor microenvironment and prognosis of hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Long Pan, Jing Fang, Ming-Yu Chen, Shu-Ting Zhai, Bin Zhang, Zhi-Yu Jiang, Sarun Juengpanich, Yi-Fan Wang and Xiu-Jun Cai |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xiu-Jun Cai, FACS, FRCS, MD, PhD, Doctor, Doctor, Professor, Surgeon, Key Laboratory of Laparoscopic Technique Research of Zhejiang Province, department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3, Qingchun East Road, Hangzhou 310016, Zhejiang Province, China. srrsh_cxj@zju.edu.cn |
| Key Words |
Hepatocellular carcinoma; Tumor microenvironment; Differentially expressed genes; Overall survival; ; |
| Core Tip |
We performed an integrated bioinformatics analysis to assess the influence of tumor microenvironment on the prognosis of patients with hepatocellular carcinoma (HCC). The results found that HCC patients with a high immune/stromal infiltration level had better survival benefits than patients with low infiltration level. Ten microenvironment-related key genes were screened and used to construct a prognostic gene signature, presenting good performance in predicting overall survival. Our study provided novel insight into the potential association of tumor microenvironment with HCC prognosis and molecular targeted therapy of HCC in the future. |
| Publish Date |
2020-02-28 03:42 |
| Citation |
Pan L, Fang J, Chen MY, Zhai ST, Zhang B, Jiang ZY, Juengpanich S, Wang YF, Cai XJ. Promising key genes associated with tumor microenvironment and the prognosis of hepatocellular carcinoma. World J Gastroenterol 2020; 26(8): 789-803 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i8/789.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i8.789 |
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